Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 2/20 | 0.47 |
| ▸ | TLR7 | Q9NYK1 | 3/20 | 0.45 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.45 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.45 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | DHFR | P00374 | 1/20 | 0.43 |
| ▸ | RNASEH1 | O60930 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.43 |
| ▸ | PARP1 | P09874 | 1/20 | 0.42 |
| ▸ | MPO | P05164 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9238060 | 0.97 | DHODH (0.48) | DHODHTLR7TLR8CYP4F2CYP4A11 | |
| SCHEMBL9231896 | 0.94 | DHODH (0.46) | DHODHTLR7TLR8CYP4F2CYP4A11 | |
| SCHEMBL9233991 | 0.89 | DHFR (0.48) | DHODHTLR7TLR8CYP4F2CYP4A11 | |
| SCHEMBL9237953 | 0.89 | DHODH (0.44) | DHODHTLR7TLR8CYP4F2CYP4A11 | |
| SCHEMBL9234662 | 0.84 | AR (0.50) | DHODHTLR7TLR8CYP4F2CYP4A11 | |
| SCHEMBL9236088 | 0.84 | LOXL2 (0.49) | DHODHCYP4F2CYP4A11POLBKMT2A | |
| SCHEMBL9237287 | 0.83 | DHFR (0.46) | DHODHTLR7TLR8CYP4F2CYP4A11 | |
| SCHEMBL9236494 | 0.82 | DHFR (0.52) | DHODHTLR7TLR8CYP4F2CYP4A11 | |
| SCHEMBL1892647 | 0.82 | IL4I1 (0.51) | POLBKMT2AL3MBTL1ALDH1A1LMNA | |
| SCHEMBL9230396 | 0.81 | AR (0.53) | DHODHCYP4A11POLBKMT2AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0685467-A1 | NOVEL PYRIMIDINE DERIVATIVE AND MEDICINAL COMPOSITION | NKK CORPORATION (JP) | 1995-12-06 | — | — | EP | disclosed |