Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 2/20 | 0.47 |
| ▸ | CES1 | P23141 | 2/20 | 0.47 |
| ▸ | PKM | P14618 | 2/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | PTGIR | P43119 | 1/20 | 0.40 |
| ▸ | OXTR | P30559 | 1/20 | 0.39 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL353571 | 0.76 | SMN1; SMN2 (0.57) | CES2CES1OPRD1LMNAMAPK1 | |
| SCHEMBL9237331 | 0.73 | CES2 (0.50) | CES2CES1LMNA | |
| SCHEMBL1198328 | 0.73 | KDM4E (0.46) | PKMHDAC1HDAC6PTGIR | |
| SCHEMBL1198330 | 0.73 | KDM4E (0.46) | PKMHDAC1HDAC6PTGIR | |
| SCHEMBL9235791 | 0.70 | CES2 (0.55) | CES2CES1LMNAMAPK1 | |
| SCHEMBL8954088 | 0.70 | CES2 (0.59) | CES2CES1LMNAMAPK1 | |
| SCHEMBL3372477 | 0.69 | HDAC1 (0.58) | PKMHDAC1HDAC6LMNA | |
| SCHEMBL9235904 | 0.68 | CES2 (0.57) | CES2CES1LMNAMAPK1 | |
| SCHEMBL241642 | 0.68 | CES2 (0.57) | CES2CES1LMNAMAPK1 | |
| Benzene SCHEMBL28201061 | 0.68 | CES2 (0.76) | CES2CES1HDAC1HDAC6LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0657452-A1 | Imidazopyridines | MERCK PATENT GmbH (DE) | 1995-06-14 | — | — | EP | disclosed |