Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 2/20 | 0.50 |
| ▸ | CES1 | P23141 | 2/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 5/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | HTT | P42858 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | GLI1 | P08151 | 1/20 | 0.43 |
| ▸ | GLI2 | P10070 | 1/20 | 0.43 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.41 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.41 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL353571 | 0.86 | SMN1; SMN2 (0.57) | CES2CES1L3MBTL1LMNASMN1; SMN2 | |
| SCHEMBL4984176 | 0.79 | TP53 (0.49) | TP53L3MBTL1LMNANPSR1SMN1; SMN2 | |
| SCHEMBL1974219 | 0.78 | TP53 (0.47) | TP53L3MBTL1LMNANPSR1SMN1; SMN2 | |
| SCHEMBL8954088 | 0.76 | CES2 (0.59) | CES2CES1LMNAKMT2AALDH1A1 | |
| SCHEMBL9231096 | 0.75 | NPC1 (0.56) | CES2CES1TP53SMN1; SMN2MAPT | |
| SCHEMBL9237328 | 0.75 | CES2 (0.48) | CES2CES1LMNASMN1; SMN2MAPT | |
| SCHEMBL8701460 | 0.75 | ALDH1A1 (0.58) | CES2CES1TP53SMN1; SMN2KMT2A | |
| SCHEMBL14228916 | 0.74 | GAA (0.44) | TP53L3MBTL1LMNANPSR1SMN1; SMN2 | |
| SCHEMBL13114813 | 0.74 | LMNA (0.45) | TP53L3MBTL1LMNANPSR1SMN1; SMN2 | |
| Alcohol SCHEMBL29064519 | 0.74 | CES2 (0.61) | CES2CES1LMNAKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0657452-A1 | Imidazopyridines | MERCK PATENT GmbH (DE) | 1995-06-14 | — | — | EP | disclosed |