SCHEMBL9237679

SCHEMBL9237679

Nc1nc(N)c2nc3nc(N)nc(N)c3nc2n1

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ADORA2A P29274 1/20 0.54
PIK3CG P48736 7/20 0.54
DHFR P00374 4/20 0.54
MEN1 O00255 1/20 0.54
MAPT P10636 1/20 0.54
BLM P54132 1/20 0.54
KMT2A Q03164 1/20 0.54
MTOR P42345 2/20 0.52
KDM4E B2RXH2 1/20 0.52
JAK2 O60674 1/20 0.52
GMNN O75496 1/20 0.52
ALDH1A1 P00352 1/20 0.52
LMNA P02545 1/20 0.52
TP53 P04637 1/20 0.52
CYP1A2 P05177 1/20 0.52
GLA P06280 1/20 0.52
CTSG P08311 1/20 0.52
CYP3A4 P08684 1/20 0.52
GAA P10253 1/20 0.52
CYP2D6 P10635 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3291956 0.91 ADORA2A (0.52) ADORA2APIK3CGDHFRMEN1MAPT
SCHEMBL2492949 0.82 DHFR (0.46) ADORA2APIK3CGDHFRMEN1MAPT
SCHEMBL24726396 0.78 PIK3CG (0.49) ADORA2APIK3CGDHFRMEN1MAPT
SCHEMBL12577476 0.78 DHFR (0.43) ADORA2APIK3CGDHFRMEN1MAPT
SCHEMBL30852975 0.77 DHFR (0.55) ADORA2APIK3CGDHFRMEN1MAPT
SCHEMBL13833398 0.77 CCNA2 (0.48) ADORA2APIK3CGDHFRMEN1MAPT
SCHEMBL9514063 0.77 PTPRF (0.45) ADORA2APIK3CGDHFRMEN1MAPT
SCHEMBL29658173 0.77 DHFR (0.55) ADORA2APIK3CGDHFRMEN1MAPT
SCHEMBL13833394 0.77 KDM4E (0.43) ADORA2APIK3CGDHFRMEN1MAPT
SCHEMBL1232461 0.77 DHFR (0.55) ADORA2APIK3CGDHFRMEN1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0682087-A1 New pigment salts and their use for dyeing and pigmenting BAYER AG (DE) 1995-11-15 EP disclosed