SCHEMBL9239334

SCHEMBL9239334

Cn1ncc(SCc2ccc(C(C)(C)C)cc2)c(Cl)c1=O

nearest known ligand 0.76

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 2/20 0.76
MEN1 O00255 1/20 0.76
NPC1 O15118 1/20 0.76
GALR3 O60755 1/20 0.76
NR2F2 P24468 1/20 0.76
GPR183 P32249 1/20 0.76
KMT2A Q03164 1/20 0.76
GPR35 Q9HC97 1/20 0.76
MAPT P10636 4/20 0.72
GAA P10253 2/20 0.72
PKM P14618 2/20 0.72
ALDH1A1 P00352 5/20 0.47
HPGD P15428 3/20 0.47
SCN9A Q15858 3/20 0.46
SCN5A Q14524 2/20 0.44
NPSR1 Q6W5P4 3/20 0.43
LMNA P02545 3/20 0.43
PPARG P37231 3/20 0.43
NCOA2 Q15596 3/20 0.43
NCOA1 Q15788 3/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Pyridaben SCHEMBL8372466 0.86 MEN1 (1.00) RAB9AMEN1NPC1GALR3NR2F2
Pyridaben SCHEMBL27429 0.86 MEN1 (1.00) RAB9AMEN1NPC1GALR3NR2F2
SCHEMBL9233697 0.85 MEN1 (0.69) RAB9AMEN1NPC1GALR3NR2F2
SCHEMBL9233692 0.84 MEN1 (0.71) RAB9AMEN1NPC1GALR3NR2F2
SCHEMBL10711762 0.84 MAPT (1.00) RAB9AMEN1NPC1GALR3NR2F2
SCHEMBL8804643 0.83 MEN1 (0.67) RAB9AMEN1NPC1GALR3NR2F2
SCHEMBL19766257 0.82 MEN1 (0.59) RAB9AMEN1NPC1GALR3NR2F2
SCHEMBL11938587 0.82 MEN1 (0.56) RAB9AMEN1NPC1GALR3NR2F2
SCHEMBL677257 0.82 RAB9A (0.68) RAB9AMEN1NPC1GALR3NR2F2
SCHEMBL9237988 0.82 KMT2A (0.68) RAB9AMEN1NPC1GALR3NR2F2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8486995-B2 Acaricidal active substance combinations BAYER CORPORATION (DE) 2013-07-16 US disclosed
US-20100216738-A1 Acaricidal Active Substance Combinations BAYER CROPSCIENCE AG (DE) 2010-08-26 US disclosed
EP-0665223-A1 Antitumor agent, novel 3(2H)-pyridazinone derivatives and their preparation TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1995-08-02 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100216738-A1 Acaricidal Active Substance Combinations DDT, ACHE, CAT RAB9A 2039/4885MEN1 3885/4885NPC1 3477/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.