Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2C known ✓ | P18825 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.68 |
| ▸ | RAB9A | P51151 | 3/20 | 0.68 |
| ▸ | NPC1 | O15118 | 2/20 | 0.68 |
| ▸ | TP53 | P04637 | 2/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.61 |
| ▸ | LMNA | P02545 | 2/20 | 0.61 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.59 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | GFER | P55789 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | DRD2 | P14416 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2621291 | 0.98 | MAPT (0.70) | MAPTRAB9ANPC1TP53SMN1; SMN2 | |
| SCHEMBL31276462 | 0.98 | MAPT (0.70) | MAPTRAB9ANPC1TP53SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL2147012 | 0.94 | RAB9A (0.66) | MAPTRAB9ANPC1TP53SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL2147139 | 0.94 | RAB9A (0.66) | MAPTRAB9ANPC1TP53SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL2147609 | 0.94 | RAB9A (0.66) | MAPTRAB9ANPC1TP53SMN1; SMN2 | |
| Acetic Acid SCHEMBL9270113 | 0.88 | NPC1 (0.58) | MAPTRAB9ANPC1TP53SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL19372018 | 0.86 | RAB9A (0.56) | MAPTRAB9ANPC1TP53SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL19372017 | 0.86 | RAB9A (0.56) | MAPTRAB9ANPC1TP53SMN1; SMN2 | |
| SCHEMBL31276277 | 0.82 | MAPT (0.78) | MAPTRAB9ANPC1TP53SMN1; SMN2 | |
| SCHEMBL1748040 | 0.82 | MAPT (0.78) | MAPTRAB9ANPC1TP53SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0672953-A2 | Photosensitive recording material, photosensitive recording medium, and process for producing hologram using this photosensitive recording medium | Toppan Printing Co., Ltd. (JP) | 1995-09-20 | — | — | EP | disclosed |