Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | KDM1A | O60341 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9239433 | 0.85 | TDP1 (0.40) | MEN1KMT2AALDH1A1SMN1; SMN2TDP1 | |
| SCHEMBL2358981 | 0.77 | HRH3 (0.39) | MEN1KMT2AALDH1A1SMN1; SMN2TDP1 | |
| SCHEMBL2358983 | 0.77 | HRH3 (0.39) | MEN1KMT2AALDH1A1SMN1; SMN2TDP1 | |
| SCHEMBL8795939 | 0.76 | CHRNB2 (0.41) | MEN1KMT2AALDH1A1TDP1 | |
| SCHEMBL8795450 | 0.76 | CHRNB2 (0.41) | MEN1KMT2AALDH1A1TDP1 | |
| SCHEMBL1410825 | 0.75 | PDE4B (0.51) | MEN1KMT2ANPSR1POLBRAB9A | |
| SCHEMBL2655142 | 0.75 | KDM1A (0.48) | MEN1KMT2ATDP1NPSR1KDM1A | |
| SCHEMBL3750998 | 0.75 | KMT2A (0.37) | MEN1KMT2AALDH1A1SMN1; SMN2TDP1 | |
| SCHEMBL3750991 | 0.75 | KMT2A (0.37) | MEN1KMT2AALDH1A1SMN1; SMN2TDP1 | |
| SCHEMBL3750983 | 0.75 | KMT2A (0.37) | MEN1KMT2AALDH1A1SMN1; SMN2TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0657455-A1 | Epi-epibatidine derivatives, a process and intermediates for preparing them and epi-epibatidine and medicaments containing the epi-epibatidine derivatives and/or epi-epibatidine and the use of them | EGIS GYOGYSZERGYAR (HU) | 1995-06-14 | — | — | EP | disclosed |