Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 2/20 | 0.48 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.43 |
| ▸ | HTR2A | P28223 | 2/20 | 0.43 |
| ▸ | HTR2C | P28335 | 2/20 | 0.43 |
| ▸ | HTR2B | P41595 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | FBP1 | P09467 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | HSPB1 | P04792 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9241939 | 0.82 | KDM1A (0.40) | KDM1ASLC6A2SLC6A4SLC6A3HTR2A | |
| SCHEMBL1524088 | 0.81 | KDM1A (0.48) | KDM1AHTR2CHTR2BMEN1KMT2A | |
| SCHEMBL2755972 | 0.81 | ALDH1A1 (0.50) | SLC6A2SLC6A4SLC6A3HTR2AHTR2C | |
| SCHEMBL17718447 | 0.81 | ALDH1A1 (0.50) | SLC6A2SLC6A4SLC6A3HTR2AHTR2C | |
| SCHEMBL12860014 | 0.81 | KDM1A (0.48) | KDM1AHTR2CHTR2BMEN1KMT2A | |
| SCHEMBL27233654 | 0.81 | ALDH1A1 (0.50) | SLC6A2SLC6A4SLC6A3HTR2AHTR2C | |
| SCHEMBL1524090 | 0.81 | KDM1A (0.48) | KDM1AHTR2CHTR2BMEN1KMT2A | |
| SCHEMBL12242256 | 0.81 | KDM1A (0.48) | KDM1AHTR2CHTR2BMEN1KMT2A | |
| SCHEMBL15024131 | 0.80 | HTR2A (0.46) | KDM1AHTR2AHTR2CHTR2BMEN1 | |
| SCHEMBL12285911 | 0.80 | HTR2A (0.46) | KDM1AHTR2AHTR2CHTR2BMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7335777-B2 | Benzimidazole derivatives and their use for modulating the GABAA receptor complex | NEUROSEARCH A/S (DK) | 2008-02-26 | — | — | US | disclosed |
| EP-1613312-B1 | BENZIMIDAZOLE DERIVATIVES AND THEIR USE FOR MODULATING THE GABA A RECEPTOR COMPLEX | NEUROSEARCH AS (DK) | 2008-02-20 | — | — | EP | disclosed |
| US-20060148856-A1 | Benzimidazole derivatives and their use for modulating the gabaa receptor complex | ANIONA APS (DK) | 2006-07-06 | — | — | US | disclosed |
| EP-1613312-A1 | BENZIMIDAZOLE DERIVATIVES AND THEIR USE FOR MODULATING THE GABA sb A /sb RECEPTOR COMPLEX | NEUROSEARCH A/S (DK) | 2006-01-11 | — | — | EP | disclosed |
| WO-2004087137-A1 | BENZIMIDAZOLE DERIVATIVES AND THEIR USE FOR MODULATING THE GABAA RECEPTOR COMPLEX | NEUROSEARCH A/S (DK) | 2004-10-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060148856-A1 | Benzimidazole derivatives and their use for modulating the gabaa receptor complex | GABRB2, GABRB1, GABRB3 | KDM1A 2289/4885SLC6A2 279/4885SLC6A4 233/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.