Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 2/20 | 0.46 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.46 |
| ▸ | HCRTR2 | O43614 | 3/20 | 0.43 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.41 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.41 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.40 |
| ▸ | KDM1A | O60341 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7948346 | 0.76 | CHRNB2 (0.62) | CHRNB2CHRNA4SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL9243087 | 0.75 | SLC6A3 (0.54) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL9240709 | 0.75 | SLC6A3 (0.54) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL7959231 | 0.75 | CHRNB2 (0.48) | CHRNB2CHRNA4SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL8299723 | 0.73 | CHRNB2 (0.66) | CHRNB2CHRNA4CHRNA3CHRNA7 | |
| SCHEMBL15006886 | 0.72 | PIK3CA (0.44) | — | |
| SCHEMBL18984025 | 0.71 | CHRNA7 (0.50) | CHRNA7KDM1ASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL18983876 | 0.71 | CHRNA7 (0.53) | CHRNA7KDM1A | |
| SCHEMBL8299717 | 0.70 | CHRM2 (0.44) | CHRNB2CHRNA4SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL669989 | 0.70 | CHRM2 (0.44) | CHRNB2CHRNA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0657455-A1 | Epi-epibatidine derivatives, a process and intermediates for preparing them and epi-epibatidine and medicaments containing the epi-epibatidine derivatives and/or epi-epibatidine and the use of them | EGIS GYOGYSZERGYAR (HU) | 1995-06-14 | — | — | EP | disclosed |