Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT2 | Q8IXJ6 | 15/20 | 0.44 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.38 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.38 |
| ▸ | NMBR | P28336 | 1/20 | 0.37 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.35 |
| ▸ | ASAH1 | Q13510 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL877052 | 0.88 | SIRT2 (0.46) | SIRT2CYP11B1CYP11B2NMBRENPP2 | |
| SCHEMBL9234830 | 0.86 | SIRT2 (0.45) | SIRT2CYP11B1CYP11B2NMBRENPP2 | |
| SCHEMBL9239498 | 0.82 | SIRT2 (0.43) | SIRT2CYP11B1CYP11B2NMBRENPP2 | |
| SCHEMBL1038850 | 0.82 | SIRT2 (0.52) | SIRT2NMBR | |
| SCHEMBL6777569 | 0.80 | SIRT2 (0.48) | SIRT2NMBR | |
| SCHEMBL1342 | 0.80 | SIRT2 (0.45) | SIRT2CYP11B1CYP11B2NMBRENPP2 | |
| SCHEMBL7988581 | 0.79 | SIRT2 (0.42) | SIRT2CYP11B1CYP11B2NMBRENPP2 | |
| SCHEMBL877785 | 0.79 | SIRT2 (0.46) | SIRT2CYP11B1CYP11B2NMBR | |
| SCHEMBL27351346 | 0.79 | SIRT2 (0.46) | SIRT2CYP11B1CYP11B2NMBRENPP2 | |
| Acetic Acid SCHEMBL7659782 | 0.79 | SIRT2 (0.47) | SIRT2CYP11B1CYP11B2NMBRENPP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0675112-A1 | Imidazole-containing inhibitors of farnesyl protein transferase | BRISTOL-MYERS SQUIBB COMPANY (US) | 1995-10-04 | — | — | EP | disclosed |