Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT2 | Q8IXJ6 | 15/20 | 0.43 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.40 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.40 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.36 |
| ▸ | NMBR | P28336 | 1/20 | 0.34 |
| ▸ | FLT3 | P36888 | 1/20 | 0.31 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.31 |
| ▸ | MERTK | Q12866 | 1/20 | 0.31 |
| ▸ | GAS6 | Q14393 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.31 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.31 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.31 |
| ▸ | GMNN | O75496 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | TRPM2 | O94759 | 1/20 | 0.31 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.31 |
| ▸ | EGFR | P00533 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9234840 | 0.85 | SIRT2 (0.46) | SIRT2CYP11B1CYP11B2ENPP2NMBR | |
| SCHEMBL877052 | 0.84 | SIRT2 (0.46) | SIRT2CYP11B1CYP11B2ENPP2NMBR | |
| SCHEMBL1041048 | 0.83 | SIRT2 (0.49) | SIRT2CYP11B1CYP11B2ENPP2NMBR | |
| SCHEMBL1342 | 0.82 | SIRT2 (0.45) | SIRT2CYP11B1CYP11B2ENPP2NMBR | |
| SCHEMBL9239485 | 0.82 | SIRT2 (0.44) | SIRT2CYP11B1CYP11B2ENPP2NMBR | |
| SCHEMBL7988581 | 0.82 | SIRT2 (0.42) | SIRT2CYP11B1CYP11B2ENPP2NMBR | |
| SCHEMBL6771514 | 0.81 | SIRT2 (0.44) | SIRT2CYP11B1CYP11B2ENPP2NMBR | |
| SCHEMBL2032778 | 0.80 | SIRT2 (0.47) | SIRT2CYP11B1CYP11B2ENPP2NMBR | |
| SCHEMBL4682888 | 0.79 | SIRT2 (0.46) | SIRT2CYP11B1CYP11B2ENPP2NMBR | |
| SCHEMBL2038903 | 0.79 | SIRT2 (0.45) | SIRT2CYP11B1CYP11B2ENPP2NMBR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0675112-A1 | Imidazole-containing inhibitors of farnesyl protein transferase | BRISTOL-MYERS SQUIBB COMPANY (US) | 1995-10-04 | — | — | EP | disclosed |