SCHEMBL9239585

SCHEMBL9239585

Oc1ccc(Cl)cc1[C]c1cc(Cl)ccc1O

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 5/20 0.54
TSHR P16473 2/20 0.54
HPGD P15428 5/20 0.50
ALOX15 P16050 4/20 0.50
ALDH1A1 P00352 3/20 0.50
ALOX12 P18054 2/20 0.50
SMN1; SMN2 Q16637 2/20 0.50
MAPK1 P28482 1/20 0.50
CYP3A4 P08684 4/20 0.48
HIF1A Q16665 4/20 0.48
MEN1 O00255 3/20 0.48
KMT2A Q03164 3/20 0.48
HSP90AA1 P07900 3/20 0.48
HTT P42858 2/20 0.48
CYP2C9 P11712 2/20 0.48
CYP2C19 P33261 2/20 0.48
LMNA P02545 2/20 0.48
MAPT P10636 2/20 0.48
HSPA5 P11021 2/20 0.48
SLC22A1 O15245 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL380452 0.83 HSD17B10 (0.44) HSD17B10TSHRHPGDALOX15ALDH1A1
SCHEMBL2809328 0.81 HSD17B10 (0.50) HSD17B10TSHRHPGDALOX15ALDH1A1
SCHEMBL5163990 0.81 HSD17B10 (0.50) HSD17B10TSHRHPGDALOX15ALDH1A1
SCHEMBL584161 0.81 HSD17B10 (0.50) HSD17B10TSHRHPGDALOX15ALDH1A1
SCHEMBL22955864 0.73 HSD17B10 (0.42) HSD17B10TSHRHPGDALOX15ALDH1A1
SCHEMBL31135339 0.73 HSD17B10 (0.42) HSD17B10TSHRHPGDALOX15ALDH1A1
SCHEMBL70036 0.73
SCHEMBL29405140 0.73
SCHEMBL25434699 0.70 HSD17B10 (0.62) HSD17B10TSHRHPGDALOX15ALDH1A1
2,4-Dichlorophenol SCHEMBL77936 0.70

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0375264-B1 Biocidal compositions ROHM & HAAS (US) 1995-01-25 EP claimed
US-5246913-A Alcohols and isothiazolones for bactericides, fungicides and algicides ROHM AND HAAS COMPANY (US) 1993-09-21 US claimed
EP-0375264-A1 Biocidal compositions ROHM AND HAAS COMPANY (US) 1990-06-27 EP claimed
EP-2917288-A1 READY-MIX JOINT COMPOUNDS USING NON-UNIFORMLY SUBSTITUTED CARBOXYMETHYLCELLULOSE Hercules Incorporated (US) 2015-09-16 EP disclosed
US-20150119490-A1 DRY MORTAR AND EMULSION/DISPERSION BASED COMPOSITIONS HERCULES INCORPORATED 2015-04-30 US disclosed
WO-2014074696-A1 READY-MIX JOINT COMPOUNDS USING NON-UNIFORMLY SUBSTITUTED CARBOXYMETHYLCELLULOSE HERCULES INCORPORATED (US) 2014-05-15 WO disclosed
US-20140135420-A1 Ready-Mix Joint Compounds Using Non-Uniformly Substituted Carboxylmethylcellulose HERCULES INCORPORATED (US) 2014-05-15 US disclosed
US-20130225732-A1 NANOCRYSTALLINECELLULOSE (NCC) IN TAPE JOINT COMPOUND (JC) HERCULES INCORPORATED (US) 2013-08-29 US disclosed
EP-0375264-B1 Biocidal compositions ROHM & HAAS (US) 1995-01-25 EP disclosed
US-5322834-A Synergistic microbicidal combinations containing 3-isothiazolin and commercial biocides ROHM AND HAAS COMPANY (US) 1994-06-21 US disclosed
US-5278178-A Ratios ROHM AND HAAS COMPANY (US) 1994-01-11 US disclosed
US-5246913-A Alcohols and isothiazolones for bactericides, fungicides and algicides ROHM AND HAAS COMPANY (US) 1993-09-21 US disclosed
US-5190944-A Bactericides or fungicides ROHM AND HAAS COMPANY (US) 1993-03-02 US disclosed
US-5132306-A Hexahydro-triethyl-triazine, treatment of industrial water systems ROHM AND HAAS COMPANY (US) 1992-07-21 US disclosed
US-4990525-A Inhibiting the growth of bacteria, fungi and algae ROHM AND HAAS COMPANY (US) 1991-02-05 US disclosed
EP-0375264-A1 Biocidal compositions ROHM AND HAAS COMPANY (US) 1990-06-27 EP disclosed
US-4906651-A Synergistic microbicidal combinations containing 3-isothiazolone and commercial biocides ROHM AND HAAS COMPANY (US) 1990-03-06 US disclosed