Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.45 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.45 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4254480 | 0.82 | HSD17B10 (0.50) | HSD17B10TSHRHPGDALOX15ALDH1A1 | |
| SCHEMBL9239585 | 0.81 | HSD17B10 (0.54) | HSD17B10TSHRHPGDALOX15ALDH1A1 | |
| SCHEMBL31441456 | 0.78 | MAOA (0.61) | HPGDALDH1A1CYP3A4MEN1KMT2A | |
| SCHEMBL7050401 | 0.78 | MAOA (0.61) | HPGDALDH1A1CYP3A4MEN1KMT2A | |
| SCHEMBL2809328 | 0.77 | HSD17B10 (0.50) | HSD17B10TSHRHPGDALOX15ALDH1A1 | |
| SCHEMBL5163990 | 0.77 | HSD17B10 (0.50) | HSD17B10TSHRHPGDALOX15ALDH1A1 | |
| SCHEMBL104941 | 0.76 | VCAM1 (0.52) | HSD17B10TSHRALDH1A1CYP3A4MAPT | |
| SCHEMBL1267040 | 0.76 | ESR2 (0.44) | ESR1ESR2CA2XDH | |
| SCHEMBL10934802 | 0.75 | ALDH1A1 (0.48) | HSD17B10TSHRALOX15ALDH1A1SMN1; SMN2 | |
| SCHEMBL14157279 | 0.75 | TTR (0.61) | HSD17B10TSHRHPGDALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 300 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090069591-A1 | Calcium Bis [ (2S) -3- [3-[ (2S) -3- (4-Chloro-2-Cyanophenoxy) -2- Fluoropropoxy]Phenyl] -2- Isopropoxypropionate] and Intermediate Thereof | EISAI R & D MANAGEMENT CO., LTD. (JP) | 2009-03-12 | — | — | US | claimed |
| CN-101163668-A | Calcium bis [ (2S) -3- [ 3- (2S) -3- (4-chloro-2-cyanophenoxy) -2-fluoropropoxy ] phenyl ] -2-isopropoxypropionate ] and intermediates thereof | EISAI CO LTD (JP) | 2008-04-16 | — | — | CN | claimed |
| EP-1873141-A1 | CALCIUM BIS[2S)-3-[3-(2S)-3-(4-CHLORO-2-CYANOPHENOXY)-2- FLUOROPROPOXY¨PHENYL]-2-ISOPROPOXYPROPIONATE] AND INTERMEDIATE THEREOF | Eisai R&D Management Co., Ltd. (JP) | 2008-01-02 | — | — | EP | claimed |
| US-20070117866-A1 | Calcium bis [ (2S) - 3- [3-[ (2S) -3- (4-chloro-2-cyanophenoxy) -2- fluoropropoxy]phenyl ]-2-isopropoxypropionate] and intermediate thereof | EISAI CO., LTD. (JP) | 2007-05-24 | — | — | US | claimed |
| JP-59095255-A | — | — | None | — | — | JP | disclosed |
| JP-59095254-A | — | — | None | — | — | JP | disclosed |
| JP-59055864-A | — | — | None | — | — | JP | disclosed |
| US-12459929-B2 | GPCR receptor agonists, pharmaceutical compositions comprising the same, and methods for their use | CARMOT THERAPEUTICS INC. (US) | 2025-11-04 | — | — | US | disclosed |
| EP-4563199-A2 | GPCR RECEPTOR AGONISTS, PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME, AND METHODS FOR THEIR USE | Carmot Therapeutics, Inc. (US) | 2025-06-04 | — | — | EP | disclosed |
| US-20250154137-A1 | GPCR RECEPTOR AGONISTS, PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME, AND METHODS FOR THEIR USE | CARMOT THERAPEUTICS, INC. | 2025-05-15 | — | — | US | disclosed |
| CN-119490424-A | Preparation method of 2-fluoro-3-aminobenzoic acid and ester compound | 沈阳中化农药化工研发有限公司 | 2025-02-21 | — | — | CN | disclosed |
| WO-2025036387-A1 | PREPARATION METHOD FOR 2-FLUORO-3-AMINOBENZOIC ACID AND ESTER COMPOUNDS | 沈阳中化农药化工研发有限公司 | 2025-02-20 | — | — | WO | disclosed |
| EP-0106588-A1 | 2-Cyano-4-halogenophenyl esters | Chisso Corporation (JP) | 1984-04-25 | — | — | EP | disclosed |
| JP-S5955864-A | ESTER OF ORTHOCYANOPHENOL | CHISSO CORP | 1984-03-31 | — | — | JP | disclosed |
| US-4418143-A | Color photographic recording material | AGFA-GEVAERT AKTIENGESELLSCHAFT (DE) | 1983-11-29 | — | — | US | disclosed |
| EP-0059354-A1 | Colour photographic recording material | Agfa-Gevaert AG (DE) | 1982-09-08 | — | — | EP | disclosed |
| US-4027018-A | INSECTICIDES, ACARACIDES, NEMATOCIDES | BAYER AKTIENGESELLSCHAFT (DT) | 1977-05-31 | — | — | US | disclosed |
| US-4000270-A | INSECTIDES, ACARICIDES, NEMATOCIDES | BAYER AKTIENGESELLSCHAFT (DT) | 1976-12-28 | — | — | US | disclosed |
| US-3996041-A | Novel amidoth ionophosphoric acid esters and their use as herbicides | BAYER AKTIENGESELLSCHAFT (DT) | 1976-12-07 | — | — | US | disclosed |
| US-3954919-A | INSECTICIDES, MITICIDES, NEMATOCIDES | BAYER AKTIENGESELLSCHAFT (DT) | 1976-05-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250154137-A1 | GPCR RECEPTOR AGONISTS, PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME, AND METHODS FOR THEIR USE | GLP1R, GCGR, GIPR | HSD17B10 2419/4885TSHR 211/4885HPGD 1729/4885 |
| US-12459929-B2 | GPCR receptor agonists, pharmaceutical compositions comprising the same, and methods for their use | GLP1R, GCGR, GIPR | HSD17B10 2419/4885TSHR 211/4885HPGD 1729/4885 |
| US-20090069591-A1 | Calcium Bis [ (2S) -3- [3-[ (2S) -3- (4-Chloro-2-Cyanophenoxy) -2- Fluoropropoxy]Phenyl] -2- Isopropoxypropionate] and Intermediate Thereof | CA2, CACNA1A, CACNA1C | HSD17B10 2419/4885TSHR 4017/4885HPGD 1770/4885 |
| US-20070117866-A1 | Calcium bis [ (2S) - 3- [3-[ (2S) -3- (4-chloro-2-cyanophenoxy) -2- fluoropropoxy]phenyl ]-2-isopropoxypropionate] and intermediate thereof | CA2, CACNA1A, CACNA1C | HSD17B10 2419/4885TSHR 4017/4885HPGD 1770/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.