Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | IDO1 | P14902 | 6/20 | 0.38 |
| ▸ | MEN1 | O00255 | 4/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.38 |
| ▸ | HTT | P42858 | 3/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | CASP1 | P29466 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22955864 | 1.00 | HSD17B10 (0.42) | HSD17B10TSHRALDH1A1HPGDALOX15 | |
| SCHEMBL15462385 | 0.81 | NR1H3 (0.43) | HSD17B10TSHRALDH1A1HPGDALOX15 | |
| SCHEMBL29172852 | 0.81 | TP53 (0.39) | HSD17B10TSHRALDH1A1CYP3A4TDP1 | |
| SCHEMBL1544552 | 0.79 | PTGDR2 (0.36) | HSD17B10TSHRALDH1A1HPGDMEN1 | |
| SCHEMBL14917306 | 0.78 | CYP3A4 (0.43) | HSD17B10TSHRALDH1A1HPGDALOX15 | |
| SCHEMBL3871076 | 0.78 | PDE10A (0.44) | HSD17B10TSHRALDH1A1HPGDALOX15 | |
| SCHEMBL17792036 | 0.78 | PYCR1 (0.31) | — | |
| SCHEMBL30250354 | 0.78 | CYP3A4 (0.43) | HSD17B10TSHRALDH1A1HPGDALOX15 | |
| SCHEMBL2462934 | 0.77 | TP53 (0.39) | HSD17B10TSHRALDH1A1HPGDALOX15 | |
| SCHEMBL25251254 | 0.76 | MAOA (0.46) | ALDH1A1HPGDMEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024222614-A1 | HETEROCYCLIC GSPT1 DEGRADATION AGENT | 北京诺诚健华医药科技有限公司 | 2024-10-31 | — | — | WO | disclosed |