Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA3 | P32297 | 5/20 | 0.59 |
| ▸ | CHRNB4 | P30926 | 4/20 | 0.59 |
| ▸ | CHRNB2 | P17787 | 3/20 | 0.58 |
| ▸ | CHRNA4 | P43681 | 3/20 | 0.58 |
| ▸ | FAAH | O00519 | 3/20 | 0.52 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.50 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.50 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.50 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.49 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.49 |
| ▸ | CHRNG | P07510 | 1/20 | 0.49 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.49 |
| ▸ | CHRND | Q07001 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9239680 | 1.00 | CHRNA3 (0.59) | CHRNA3CHRNB4CHRNB2CHRNA4FAAH | |
| SCHEMBL9244564 | 0.92 | CHRNB4 (0.54) | CHRNA3CHRNB4CHRNB2CHRNA4FAAH | |
| SCHEMBL9244561 | 0.92 | CHRNB4 (0.54) | CHRNA3CHRNB4CHRNB2CHRNA4FAAH | |
| SCHEMBL9243580 | 0.91 | CHRNB4 (0.62) | CHRNA3CHRNB4CHRNB2CHRNA4FAAH | |
| SCHEMBL9239052 | 0.91 | CHRNB4 (0.62) | CHRNA3CHRNB4CHRNB2CHRNA4FAAH | |
| SCHEMBL9239044 | 0.91 | CHRNB4 (0.62) | CHRNA3CHRNB4CHRNB2CHRNA4FAAH | |
| Hydrochloric Acid SCHEMBL9240142 | 0.90 | CHRNB4 (0.61) | CHRNA3CHRNB4CHRNB2CHRNA4FAAH | |
| Hydrochloric Acid SCHEMBL9243429 | 0.90 | CHRNB4 (0.61) | CHRNA3CHRNB4CHRNB2CHRNA4FAAH | |
| Hydrochloric Acid SCHEMBL9240140 | 0.90 | CHRNB4 (0.61) | CHRNA3CHRNB4CHRNB2CHRNA4FAAH | |
| SCHEMBL28821033 | 0.83 | CHRNB4 (0.56) | CHRNA3CHRNB4CHRNB2CHRNA4FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5472958-A | 2-((nitro)phenoxymethyl) heterocyclic compounds that enhance cognitive function | ABBOTT LABORATORIES (US) | 1995-12-05 | — | — | US | claimed |
| US-5472958-A | 2-((nitro)phenoxymethyl) heterocyclic compounds that enhance cognitive function | ABBOTT LABORATORIES (US) | 1995-12-05 | — | — | US | disclosed |