Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.67 |
| ▸ | NPC1 | O15118 | 4/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.67 |
| ▸ | MEN1 | O00255 | 1/20 | 0.67 |
| ▸ | GALR3 | O60755 | 1/20 | 0.67 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.67 |
| ▸ | GPR183 | P32249 | 1/20 | 0.67 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.67 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | PKM | P14618 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.41 |
| ▸ | HTT | P42858 | 4/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | JAK2 | O60674 | 1/20 | 0.41 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.41 |
| ▸ | XBP1 | P17861 | 1/20 | 0.41 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9240139 | 0.91 | KMT2A (0.70) | RAB9ANPC1KMT2AMEN1GALR3 | |
| SCHEMBL10700020 | 0.86 | NPC1 (0.71) | RAB9ANPC1KMT2AMEN1GALR3 | |
| SCHEMBL29034522 | 0.86 | NPC1 (0.71) | RAB9ANPC1KMT2AMEN1GALR3 | |
| SCHEMBL9238698 | 0.83 | RAB9A (0.67) | RAB9ANPC1KMT2AMEN1GALR3 | |
| SCHEMBL9775193 | 0.83 | NPC1 (0.81) | RAB9ANPC1KMT2AMEN1GALR3 | |
| SCHEMBL29034524 | 0.82 | NPC1 (0.69) | RAB9ANPC1KMT2AMEN1GALR3 | |
| SCHEMBL9238687 | 0.82 | NPC1 (0.57) | RAB9ANPC1KMT2AMEN1GALR3 | |
| SCHEMBL9240100 | 0.81 | NPC1 (0.82) | RAB9ANPC1KMT2AMEN1GALR3 | |
| SCHEMBL9625863 | 0.81 | KMT2A (0.67) | RAB9ANPC1KMT2AMEN1GALR3 | |
| SCHEMBL9625865 | 0.81 | KMT2A (0.67) | RAB9ANPC1KMT2AMEN1GALR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0665223-A1 | Antitumor agent, novel 3(2H)-pyridazinone derivatives and their preparation | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1995-08-02 | — | — | EP | disclosed |