Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 5/20 | 0.36 |
| ▸ | KCNH3 | Q9ULD8 | 1/20 | 0.35 |
| ▸ | KDM1A | O60341 | 1/20 | 0.34 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.34 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.34 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 3/20 | 0.34 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9242170 | 0.84 | MAPT (0.43) | MAPTSMN1; SMN2ALDH1A1KMT2AMAPK1 | |
| SCHEMBL9239787 | 0.82 | MAPT (0.33) | MAPTSMN1; SMN2ALDH1A1KMT2AMAPK1 | |
| SCHEMBL9241135 | 0.80 | HRH2 (0.43) | MAPTSMN1; SMN2ALDH1A1KMT2AMAPK1 | |
| SCHEMBL9871503 | 0.77 | KDM4A (0.33) | MAPTSMN1; SMN2ALDH1A1MAPK1GAA | |
| SCHEMBL9285075 | 0.77 | KDM4E (0.46) | ALDH1A1KMT2AGAAKDM1AADRA2A | |
| SCHEMBL501958 | 0.70 | CNR2 (0.49) | MAPTSMN1; SMN2ALDH1A1KMT2AMAPK1 | |
| SCHEMBL11726260 | 0.70 | MAPT (0.44) | MAPTSMN1; SMN2ALDH1A1KMT2AMAPK1 | |
| SCHEMBL13006705 | 0.69 | MAPT (0.43) | MAPTSMN1; SMN2ALDH1A1KMT2AMAPK1 | |
| Diphenylamine SCHEMBL28868778 | 0.68 | HSD17B10 (0.60) | MAPTSMN1; SMN2ALDH1A1KMT2AMAPK1 | |
| Diphenylamine SCHEMBL27507095 | 0.68 | HSD17B10 (0.60) | MAPTSMN1; SMN2ALDH1A1KMT2AMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0278890-B1 | Non-staining and slightly-staining antiozonants | GOODYEAR TIRE & RUBBER (US) | 1995-05-24 | — | — | EP | claimed |
| US-5019611-A | Tetrahydrotriazinethiones | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1991-05-28 | — | — | US | claimed |
| EP-0278890-B1 | Non-staining and slightly-staining antiozonants | GOODYEAR TIRE & RUBBER (US) | 1995-05-24 | — | — | EP | disclosed |
| US-5019611-A | Tetrahydrotriazinethiones | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1991-05-28 | — | — | US | disclosed |
| EP-0278890-A2 | Non-staining and slightly-staining antiozonants | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1988-08-17 | — | — | EP | disclosed |