Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.33 |
| ▸ | NPC1 | O15118 | 3/20 | 0.33 |
| ▸ | RAB9A | P51151 | 3/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.33 |
| ▸ | RELA | Q04206 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.30 |
| ▸ | LMNA | P02545 | 2/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.30 |
| ▸ | RECQL | P46063 | 1/20 | 0.30 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9243090 | 0.84 | MAPT (0.35) | MAPTATM | |
| SCHEMBL9240992 | 0.82 | MAPT (0.38) | MAPTSMN1; SMN2RAB9AKMT2AALDH1A1 | |
| SCHEMBL9241807 | 0.80 | GAA (0.38) | MAPTSMN1; SMN2NPC1RAB9ATP53 | |
| SCHEMBL9242374 | 0.80 | MAPT (0.35) | MAPTSMN1; SMN2TP53KMT2AALDH1A1 | |
| SCHEMBL9245105 | 0.77 | MEN1 (0.35) | MAPTSMN1; SMN2NPC1RAB9AKMT2A | |
| SCHEMBL9871503 | 0.77 | KDM4A (0.33) | MAPTSMN1; SMN2NPC1RAB9ATP53 | |
| SCHEMBL9242170 | 0.67 | MAPT (0.43) | MAPTSMN1; SMN2NPC1RAB9AKMT2A | |
| SCHEMBL5358581 | 0.66 | TSHR (0.38) | THRBTSHR | |
| SCHEMBL12965949 | 0.65 | ALDH1A1 (0.42) | MAPTSMN1; SMN2NPC1RAB9AKMT2A | |
| SCHEMBL24590408 | 0.65 | MAPT (0.59) | MAPTSMN1; SMN2NPC1RAB9ATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0278890-B1 | Non-staining and slightly-staining antiozonants | GOODYEAR TIRE & RUBBER (US) | 1995-05-24 | — | — | EP | claimed |
| US-5019611-A | Tetrahydrotriazinethiones | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1991-05-28 | — | — | US | claimed |
| EP-0278890-A2 | Non-staining and slightly-staining antiozonants | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1988-08-17 | — | — | EP | claimed |
| EP-0278890-B1 | Non-staining and slightly-staining antiozonants | GOODYEAR TIRE & RUBBER (US) | 1995-05-24 | — | — | EP | disclosed |
| US-5019611-A | Tetrahydrotriazinethiones | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1991-05-28 | — | — | US | disclosed |