Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.37 |
| ▸ | CYP11B1 | P15538 | 3/20 | 0.36 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.34 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.34 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.34 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | KIF11 | P52732 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11891091 | 0.83 | CYP11B1 (0.39) | ALDH1A1TDP1PTGS2CYP11B1CYP11B2 | |
| SCHEMBL25368788 | 0.77 | TAAR1 (0.42) | ALDH1A1TDP1PTGS2CYP11B1CYP11B2 | |
| SCHEMBL13089069 | 0.76 | CYP11B1 (0.39) | TDP1PTGS2CYP11B1CYP11B2CYP1A2 | |
| SCHEMBL25368110 | 0.76 | CYP11B1 (0.36) | ALDH1A1TDP1CYP11B1CYP11B2CYP2D6 | |
| SCHEMBL11891102 | 0.75 | SMN1; SMN2 (0.42) | ALDH1A1TDP1CYP11B1CYP11B2SMN1; SMN2 | |
| SCHEMBL11891094 | 0.75 | ALDH1A1 (0.41) | ALDH1A1TDP1CYP11B1CYP11B2CYP1A2 | |
| SCHEMBL27804377 | 0.74 | CYP11B1 (0.40) | ALDH1A1TDP1PTGS2CYP11B1CYP11B2 | |
| SCHEMBL7683395 | 0.74 | ALDH1A1 (0.46) | ALDH1A1TDP1PTGS2CYP11B1CYP11B2 | |
| SCHEMBL23704552 | 0.73 | HSP90AA1 (0.40) | TDP1PTGS2CYP11B1CYP11B2CYP1A2 | |
| SCHEMBL13089068 | 0.72 | TDP1 (0.41) | ALDH1A1TDP1PTGS2CYP11B1CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0675112-A1 | Imidazole-containing inhibitors of farnesyl protein transferase | BRISTOL-MYERS SQUIBB COMPANY (US) | 1995-10-04 | — | — | EP | disclosed |