SCHEMBL924167

SCHEMBL924167

O=[N+]([O-])CN1CCCCS1

nearest known ligand 0.30

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.30
MAPT P10636 1/20 0.30
MAPK1 P28482 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30
TDP1 Q9NUW8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13976104 0.66
SCHEMBL11952835 0.62 ALDH1A1 (0.32) ALDH1A1
SCHEMBL20214885 0.55 HRH3 (0.48) ALDH1A1MAPTSMN1; SMN2TDP1
SCHEMBL4366628 0.53
Tetrahydrothiophene SCHEMBL6281398 0.53 MEN1 (0.38) ALDH1A1MAPT
SCHEMBL2347952 0.51
SCHEMBL18561592 0.51 MAPT (0.32) MAPT
SCHEMBL6050507 0.51 MAPT (0.37) ALDH1A1MAPTMAPK1SMN1; SMN2TDP1
SCHEMBL3795933 0.47
SCHEMBL15750425 0.46

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 307 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1507761-B1 PYRIDINE CARBOXAMIDE DERIVATIVES AND THEIR USE AS PESTICIDES MERIAL INC (US) 2016-02-24 EP disclosed
EP-1569517-B1 PESTICIDAL 5- (ACYLAMINO) PYRAZOLE DERIVATIVES MERIAL LTD (US) 2013-10-02 EP disclosed
EP-1599451-B1 PESTICIDAL 1-ARYL-3-AMIDOXIME-PYRAZOLE DERIVATIVES MERIAL LTD (US) 2013-04-24 EP disclosed
EP-1663986-B1 PESTICIDAL 5-SUBSTITUTED-OXYALKYLAMINO-1-ARYLPYRAZOLE DERIVATIVES MERIAL LTD (US) 2013-03-27 EP disclosed
EP-1569910-B1 PESTICIDAL SULPHONYLAMINOPYRAZOLES MERIAL LTD (US) 2011-03-09 EP disclosed
US-7879897-B2 Pesticidal 5-substituted-oxyalkylamino-1-arylpyrazole derivatives MERIAL LIMITED (US) 2011-02-01 US disclosed
US-7872038-B2 Low dosage oral veterinary medication; insects, arachnids and helminths MERIAL LIMITED (US) 2011-01-18 US disclosed
EP-1730115-B1 5-AMINOALKYLPYRAZOLE DERIVATIVES AS PESTICIDAL AGENTS MERIAL LTD (US) 2010-06-09 EP disclosed
US-7659288-B2 5-[N-Methyl-N-(phthalimidomethyl)amino]-1-(2,6-dichloro-4-trifluoromethylphenyl)-3-cyano-4-trifluoromethylsulfinylpyrazole; used in oral form so as to prevent the possible contamination of humans or the surrounding environment; used in lower dose MERIAL LIMITED (US) 2010-02-09 US disclosed
US-7629348-B2 Heterocyclic amide and imine derivatives, processes for their preparation, compositions comprising them and their use as pesticides MERIAL LIMITED (US) 2009-12-08 US disclosed
US-4954529-A MITICIDES, INSECTICIDES HOECHST AKTIENGESELLSCHAFT (DE) 1990-09-04 US disclosed
EP-0382112-A2 Pyrimidine trione derivatives, process for their preparation, agents containing them, and their use as parasiticides HOECHST AKTIENGESELLSCHAFT (DE) 1990-08-16 EP disclosed
EP-0336199-A1 Azaneophyl and silazaneophyl sulfides, process for their preparation, agents containing them, and their use as pesticides HOECHST AKTIENGESELLSCHAFT (DE) 1989-10-11 EP disclosed
US-4855309-A Pyridine derivatives, agents containing same, and the use thereof as pesticides HOECHST AKTIENGESELLSCHAFT (DE) 1989-08-08 US disclosed
EP-0318882-A2 (Thio)benzoyl ureas, functional derivatives, process for their preparation, compositions and pesticidal use HOECHST AKTIENGESELLSCHAFT (DE) 1989-06-07 EP disclosed
EP-0317881-A2 Pyridyl- and pyrazinyl compounds, process for their preparation, composition containing them and their use as fungicides HOECHST AKTIENGESELLSCHAFT (DE) 1989-05-31 EP disclosed
EP-0311962-A2 Pyridil phosphates, process for their preparation, composition containing them and its use as a pesticide HOECHST AKTIENGESELLSCHAFT (DE) 1989-04-19 EP disclosed
EP-0243790-A1 N-phenyl(thio)ureas and their functional derivatives, processes for their production and their use as pesticides HOECHST AKTIENGESELLSCHAFT (DE) 1987-11-04 EP disclosed
EP-0227046-A2 Pyridine derivatives, process for their preparation, agents containing them and their use as pesticides HOECHST AKTIENGESELLSCHAFT (DE) 1987-07-01 EP disclosed
EP-0199945-A2 Carbamoylarylcarboximide-acid esters, process for their preparation, compositions containing them and their use as pesticides HOECHST AKTIENGESELLSCHAFT (DE) 1986-11-05 EP disclosed