Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 2/20 | 0.60 |
| ▸ | CHRNA3 | P32297 | 4/20 | 0.56 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9241903 | 1.00 | LTA4H (0.60) | LTA4HCHRNA3CHRNB4 | |
| Hydrochloric Acid SCHEMBL9242432 | 0.98 | LTA4H (0.58) | LTA4HCHRNA3CHRNB4 | |
| Hydrochloric Acid SCHEMBL9242435 | 0.98 | LTA4H (0.58) | LTA4HCHRNA3CHRNB4 | |
| SCHEMBL9241944 | 0.84 | CHRNB4 (0.70) | LTA4HCHRNA3CHRNB4 | |
| SCHEMBL4664872 | 0.84 | CHRNB4 (0.70) | LTA4HCHRNA3CHRNB4 | |
| SCHEMBL9241941 | 0.84 | CHRNB4 (0.70) | LTA4HCHRNA3CHRNB4 | |
| SCHEMBL8290117 | 0.83 | LTA4H (0.83) | LTA4HCHRNA3 | |
| SCHEMBL7409154 | 0.83 | CHRNB4 (0.71) | CHRNA3CHRNB4 | |
| Hydrochloric Acid SCHEMBL9244609 | 0.83 | CHRNB4 (0.68) | LTA4HCHRNA3CHRNB4 | |
| Hydrochloric Acid SCHEMBL9238658 | 0.83 | CHRNB4 (0.68) | LTA4HCHRNA3CHRNB4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5472958-A | 2-((nitro)phenoxymethyl) heterocyclic compounds that enhance cognitive function | ABBOTT LABORATORIES (US) | 1995-12-05 | — | — | US | claimed |
| US-5472958-A | 2-((nitro)phenoxymethyl) heterocyclic compounds that enhance cognitive function | ABBOTT LABORATORIES (US) | 1995-12-05 | — | — | US | disclosed |