Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNP | P00491 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | PDE4A | P27815 | 2/20 | 0.46 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.46 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.46 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.46 |
| ▸ | PDE5A | O76074 | 1/20 | 0.46 |
| ▸ | TYMS | P04818 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | CASP1 | P29466 | 1/20 | 0.43 |
| ▸ | CASP7 | P55210 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | QTRT1 | Q9BXR0 | 1/20 | 0.42 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3303803 | 0.86 | PNP (0.44) | PNPKDM4EPDE4APDE4BPDE4C | |
| SCHEMBL17186438 | 0.86 | QTRT1 (0.44) | PNPKDM4ENPC1PDE4APDE4B | |
| Hydrochloric Acid SCHEMBL17186517 | 0.85 | QTRT1 (0.43) | PNPKDM4ENPC1PDE4APDE4B | |
| Hydrochloric Acid SCHEMBL17186488 | 0.85 | PNP (0.43) | PNPKDM4EPDE4APDE4BPDE4C | |
| Hydrochloric Acid SCHEMBL17186508 | 0.85 | PNP (0.47) | PNPKDM4ENPC1PDE4APDE4B | |
| SCHEMBL3308556 | 0.85 | PNP (0.45) | PNPKDM4ENPC1PDE4APDE4B | |
| SCHEMBL1262618 | 0.85 | PNP (0.45) | PNPKDM4EPDE4APDE4BPDE4C | |
| SCHEMBL3310264 | 0.84 | PNP (0.44) | PNPKDM4EPDE4APDE4BPDE4C | |
| SCHEMBL1533545 | 0.84 | MPO (0.48) | PNPPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL3021036 | 0.84 | PNP (0.44) | PNPKDM4EPDE4APDE4BPDE4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-7278146-A | — | — | None | — | — | JP | disclosed |
| JP-H07278146-A | BENZYLGUANINE DERIVATIVE | TOAGOSEI CO LTD | 1995-10-24 | — | — | JP | disclosed |