SCHEMBL9242593

SCHEMBL9242593

Nc1nc([S])cs1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10719025 0.73 ALDH1A1 (0.61)
SCHEMBL461605 0.71
Hydrochloric Acid SCHEMBL20475963 0.69
Bromide SCHEMBL19681460 0.69 SMN1; SMN2 (0.52)
SCHEMBL10403992 0.67
SCHEMBL10403990 0.67
SCHEMBL11444444 0.67
SCHEMBL6311788 0.67
SCHEMBL48592 0.67
SCHEMBL4469860 0.67

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0347840-B1 Phosphinic acid derivates BANYU PHARMA CO LTD (JP) 1995-12-27 EP disclosed
US-4988681-A Dipeptidase inhibitore; reducing renal toxicity; prevention deactivation of (carba)penem antibiotics BANYU PHARMACEUTICAL CO., LTD. (JP) 1991-01-29 US disclosed
EP-0347840-A2 Phosphinic acid derivates BANYU PHARMACEUTICAL CO., LTD. (JP) 1989-12-27 EP disclosed
EP-0303172-A2 Oxyimino-cephalosporins F. HOFFMANN-LA ROCHE AG (CH) 1989-02-15 EP disclosed