Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 4/20 | 0.54 |
| ▸ | AGTR2 | P50052 | 3/20 | 0.54 |
| ▸ | AGT | P01019 | 2/20 | 0.52 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9053261 | 0.95 | AGTR1 (0.60) | AGTR1AGTR2AGTACHELMNA | |
| SCHEMBL9248172 | 0.93 | AGTR1 (0.54) | AGTR1AGTR2AGTACHELMNA | |
| SCHEMBL9142860 | 0.88 | AGTR1 (0.54) | AGTR1AGTR2AGT | |
| SCHEMBL1966667 | 0.83 | AGTR1 (0.54) | AGTR1AGTR2AGT | |
| SCHEMBL1968567 | 0.83 | AGTR1 (0.54) | AGTR1AGTR2AGT | |
| SCHEMBL9042305 | 0.83 | AGTR1 (0.59) | AGTR1AGTR2AGT | |
| SCHEMBL9402059 | 0.82 | AGTR1 (0.53) | AGTR1AGTR2AGT | |
| SCHEMBL9044274 | 0.82 | AGT (0.51) | AGTR1AGTR2AGT | |
| SCHEMBL9025803 | 0.81 | AGTR1 (0.52) | AGTR1AGTR2AGT | |
| SCHEMBL9025737 | 0.81 | AGTR1 (0.51) | AGTR1AGTR2AGT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5424316-A | Imidazopyridine derivatives for the treatment of hypertension | TANABE SEIYAKU CO., LTD. (JP) | 1995-06-13 | — | — | US | disclosed |
| US-5409936-A | Useful in prophylaxix; exhibits potent angiotensin ii inhibitory acivities | TANABE SEIYAKU CO., LTD. (JP) | 1995-04-25 | — | — | US | disclosed |
| EP-0531874-A1 | Imidazopyridine derivatives and process for preparation thereof | TANABE SEIYAKU CO., LTD. (JP) | 1993-03-17 | — | — | EP | disclosed |