Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NQO1 | P15559 | 1/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | LTA4H | P09960 | 4/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.44 |
| ▸ | RELA | Q04206 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6468174 | 0.93 | NQO1 (0.61) | NQO1KDM4EALDH1A1SMN1; SMN2TDP1 | |
| SCHEMBL11042247 | 0.88 | NQO1 (0.67) | NQO1KDM4EALDH1A1SMN1; SMN2TDP1 | |
| SCHEMBL8778513 | 0.88 | LTA4H (0.57) | SMN1; SMN2TSHRLTA4HNPC1LMNA | |
| SCHEMBL6470736 | 0.86 | LTA4H (0.53) | SMN1; SMN2TSHRLTA4HNPC1LMNA | |
| 1-Butyloxy-4-Ethoxybenzene SCHEMBL27940791 | 0.84 | NQO1 (0.67) | NQO1KDM4EALDH1A1SMN1; SMN2TDP1 | |
| SCHEMBL7323818 | 0.84 | MAPK1 (0.58) | KDM4EALDH1A1TDP1TSHRLMNA | |
| SCHEMBL14984021 | 0.83 | NQO1 (0.74) | NQO1KDM4EALDH1A1SMN1; SMN2TDP1 | |
| 1-Butyloxy-4-Ethoxybenzene SCHEMBL14695816 | 0.83 | NQO1 (0.74) | NQO1KDM4EALDH1A1SMN1; SMN2TDP1 | |
| SCHEMBL11046727 | 0.83 | NR5A1 (0.66) | TSHRLTA4HNPC1LMNAMAPT | |
| SCHEMBL1047649 | 0.82 | DRD2 (0.52) | ALDH1A1SMN1; SMN2TDP1NPC1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5447900-A | Fluoran leuco dye and developer | RICOH COMPANY, LTD. (JP) | 1995-09-05 | — | — | US | disclosed |