⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1879279 | 0.73 | CYP2C19 (0.35) | — | |
| SCHEMBL3944202 | 0.67 | CRBN (0.32) | — | |
| SCHEMBL775170 | 0.67 | TRIM24 (0.32) | — | |
| SCHEMBL16058946 | 0.67 | — | — | |
| SCHEMBL28645452 | 0.67 | — | — | |
| SCHEMBL22020336 | 0.64 | — | — | |
| SCHEMBL9700492 | 0.63 | EGLN1 (0.33) | — | |
| SCHEMBL1148096 | 0.61 | SMN1; SMN2 (0.40) | — | |
| SCHEMBL21338347 | 0.61 | MEN1 (0.32) | — | |
| SCHEMBL1743259 | 0.61 | TLR4 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0614373-A4 | ORAL PHARMACEUTICAL COMPOSITION CONTAINING POLYETHYLENE GLYCOL IMMUNOGLOBULIN CONJUGATE. | SINAI SCHOOL MEDICINE (US) | 1995-01-18 | — | — | EP | disclosed |
| EP-0614373-A1 | ORAL PHARMACEUTICAL COMPOSITION CONTAINING POLYETHYLENE GLYCOL IMMUNOGLOBULIN CONJUGATE | MOUNT SINAI SCHOOL OF MEDICINE OF THE CITY UNIVERSITY OF NEW YORK (US) | 1994-09-14 | — | — | EP | disclosed |
| WO-1993008838-A1 | ORAL PHARMACEUTICAL COMPOSITION CONTAINING POLYETHYLENE GLYCOL IMMUNOGLOBULIN CONJUGATE | MOUNT SINAI SCHOOL OF MEDICINE OF THE CITY UNIVERSITY OF NEW YORK (US) | 1993-05-13 | — | — | WO | disclosed |
| US-5169627-A | Having resistance to degradation by intestinal enzymes while retaining immunological activity | MOUNT SINAI SCHOOL OF MEDICINE OF THE CITY UNIVERSITY OF NEW YORK (US) | 1992-12-08 | — | — | US | disclosed |