SCHEMBL3944202

SCHEMBL3944202

NC(=O)[C@H]1NC(=O)CCC1=O

nearest known ligand 0.32

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
CRBN Q96SW2 1/20 0.32
PARP1 P09874 1/20 0.31
PARP2 Q9UGN5 1/20 0.31
ITGB3 P05106 1/20 0.30
ITGB2 P05107 1/20 0.30
ITGB1 P05556 1/20 0.30
ITGAV P06756 1/20 0.30
ITGA2B P08514 1/20 0.30
ITGA5 P08648 1/20 0.30
ITGB5 P18084 1/20 0.30
ITGAL P20701 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9172323 0.87 CRBN (0.33) CRBNPARP1PARP2
SCHEMBL737201 0.82 ITGB3 (0.34) CRBNITGB3ITGB2ITGB1ITGAV
SCHEMBL17983759 0.73
SCHEMBL1050924 0.73
SCHEMBL1050921 0.73
SCHEMBL9699985 0.70 MCL1 (0.34) CRBNITGB3ITGB2ITGB1ITGAV
SCHEMBL24111715 0.70 MEN1 (0.31) ITGB3ITGAVITGA2BITGB5
SCHEMBL9699954 0.68 KMT2A (0.33) CRBNITGB3ITGB2ITGB1ITGAV
SCHEMBL2274342 0.68 KMT2A (0.33) CRBNITGB3ITGB2ITGB1ITGAV
SCHEMBL9699920 0.68 KMT2A (0.33) CRBNITGB3ITGB2ITGB1ITGAV

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1948819-B1 DIAMINE OXIDASE DETERMINATION SCIOTEC DIAGNOSTIC TECHNOLOGIE (AT) 2009-04-15 EP disclosed
EP-0161195-B1 METHOD FOR THE IMMUNOLOGICAL DETERMINATION OF MONOAMINES Société Anonyme dite: IMMUNOTECH (FR) 1989-07-19 EP disclosed
US-4818683-A Immunoassay for monoamines IMMUNOTECH (FR) 1989-04-04 US disclosed
EP-0161195-A1 Method for the immunological determination of monoamines Société Anonyme dite: IMMUNOTECH (FR) 1985-11-13 EP disclosed