SCHEMBL9243252

SCHEMBL9243252

CC1(C)CC(C(CCCCCCCC(=O)O)(C(=O)O)C2CC(C)(C)N(Cc3ccccc3)C(C)(C)C2)CC(C)(C)N1Cc1ccccc1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.40
RXFP1 Q9HBX9 1/20 0.40
ABL1 P00519 1/20 0.36
RIN1 Q13671 1/20 0.36
ARG1 P05089 2/20 0.35
ARG2 P78540 2/20 0.35
HDAC3 O15379 2/20 0.35
HDAC4 P56524 2/20 0.35
HDAC1 Q13547 2/20 0.35
HDAC7 Q8WUI4 2/20 0.35
HDAC2 Q92769 2/20 0.35
HDAC10 Q969S8 2/20 0.35
HDAC11 Q96DB2 2/20 0.35
HDAC8 Q9BY41 2/20 0.35
HDAC6 Q9UBN7 2/20 0.35
HDAC9 Q9UKV0 2/20 0.35
HDAC5 Q9UQL6 2/20 0.35
MAPK1 P28482 1/20 0.35
ADRA1A P35348 1/20 0.35
SLC6A3 Q01959 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL209037 0.84 MAPT (0.37) MAPTRXFP1MAPK1SMN1; SMN2THRB
SCHEMBL11178903 0.82 HDAC3 (0.40) MAPTRXFP1HDAC3HDAC4HDAC1
Sebacic Acid SCHEMBL9813717 0.82 MAPT (0.46) MAPTRXFP1ABL1RIN1HDAC3
Sebacic Acid SCHEMBL10676479 0.82 MAPT (0.46) MAPTRXFP1ABL1RIN1HDAC3
SCHEMBL6492997 0.81 PTGFR (0.37) MAPTRXFP1HDAC3HDAC4HDAC1
SCHEMBL16701758 0.81 ALDH1A1 (0.35) MAPTRXFP1HDAC3HDAC4HDAC1
SCHEMBL4135294 0.80 TSHR (0.33) HDAC11ALDH1A1TSHRLMNAHSD17B10
SCHEMBL6365851 0.80 HTT (0.38) MAPTRXFP1MAPK1SMN1; SMN2ALDH1A1
SCHEMBL11166300 0.80 MAPT (0.44) MAPTRXFP1ABL1RIN1HDAC3
SCHEMBL10903758 0.79 GAA (0.35) MAPTRXFP1HDAC3HDAC4HDAC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0237485-B1 Stabilized compositions of rigid PVC CIBA GEIGY AG (CH) 1995-01-18 EP claimed
US-4822833-A USING A MIXTURE OF A 2,2,6,6-TETRAALKYLPIPERIDINE AND AN ORGANOTIN CARBOXYLATE THERMAL STABILIZER; REDUCED TITANIUM OXIDE LEVELS; WEATHERPROOFING CIBA-GEIGY CORPORATION (US) 1989-04-18 US claimed
EP-0237485-A2 Stabilized compositions of rigid PVC CIBA-GEIGY AG (CH) 1987-09-16 EP claimed
EP-0237485-B1 Stabilized compositions of rigid PVC CIBA GEIGY AG (CH) 1995-01-18 EP disclosed
EP-0237485-A2 Stabilized compositions of rigid PVC CIBA-GEIGY AG (CH) 1987-09-16 EP disclosed
EP-0016723-B2 LIGHT STABILISATION OF TWO-LAYER COMPOSITE LACQUERS CIBA-GEIGY AG (CH) 1987-09-16 EP disclosed
EP-0155912-A2 Radiation-stabilized polymer compositions CIBA-GEIGY AG (CH) 1985-09-25 EP disclosed
US-RE31343-E STABILIZERS FOR POLYMERS CIBA-GEIGY CORPORATION (US) 1983-08-09 US disclosed
US-RE31342-E STABILIZERS FOR POLYMERS CIBA-GEIGY CORPORATION (US) 1983-08-09 US disclosed
EP-0016723-B1 LIGHT STABILISATION OF TWO-LAYER COMPOSITE LACQUERS CIBA-GEIGY AG (CH) 1983-06-01 EP disclosed
EP-0015230-B1 STABILIZED ORGANIC POLYMER COMPRISING 2-(2-HYDROXY-3,5-DI-TERT-OCTYLPHENYL)-2H-BENZOTRIAZOLE AS A LIGHT-STABILIZER CIBA-GEIGY AG (CH) 1983-02-23 EP disclosed
EP-0007468-B1 COMPOSITIONS PHOTODURCISSABLES CIBA-GEIGY AG (CH) 1982-04-07 EP disclosed
EP-0006564-B1 2-(3.5-DISUBSTITUTED-2-HYDROXYPHENYL)-2H-BENZOTRIAZOLES AND STABILIZED COMPOSITIONS CONTAINING THEM CIBA-GEIGY AG (CH) 1981-12-30 EP disclosed
US-4279720-A PHENYLGLYOXYLATE PHOTOINITIATOR WITH POLYALKYLPIPERIDINE STABILIZER CIBA-GEIGY CORPORATION (US) 1981-07-21 US disclosed
EP-0007059-B1 PHOTOCURABLE COMPOSITIONS CIBA-GEIGY AG (CH) 1981-04-15 EP disclosed
EP-0016723-A1 Light stabilisation of two-layer composite lacquers CIBA-GEIGY AG (CH) 1980-10-01 EP disclosed
EP-0015230-A1 Stabilized organic Polymer comprising 2-(2-hydroxy-3,5-di-tert-octylphenyl)-2H-benzotriazole as a light-stabilizer CIBA-GEIGY AG (CH) 1980-09-03 EP disclosed
EP-0006564-A2 2-(3.5-disubstituted-2-hydroxyphenyl)-2H-benzotriazoles and stabilized compositions containing them CIBA-GEIGY AG (CH) 1980-01-09 EP disclosed