Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.33 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.33 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.33 |
| ▸ | PPARG | P37231 | 7/20 | 0.33 |
| ▸ | PPARD | Q03181 | 7/20 | 0.33 |
| ▸ | PPARA | Q07869 | 7/20 | 0.33 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | TLR2 | O60603 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | FABP4 | P15090 | 2/20 | 0.33 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.33 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5448887 | 0.87 | TSHR (0.34) | TSHRLMNANFKB1PMP22TBXAS1 | |
| SCHEMBL5450327 | 0.87 | TSHR (0.34) | TSHRLMNANFKB1PMP22TBXAS1 | |
| SCHEMBL316765 | 0.87 | TSHR (0.34) | TSHRLMNANFKB1PMP22TBXAS1 | |
| SCHEMBL34980 | 0.87 | TSHR (0.34) | TSHRLMNANFKB1PMP22TBXAS1 | |
| SCHEMBL5453694 | 0.87 | TSHR (0.34) | TSHRLMNANFKB1PMP22TBXAS1 | |
| SCHEMBL9466511 | 0.87 | TSHR (0.34) | TSHRLMNANFKB1PMP22TBXAS1 | |
| Hydrochloric Acid SCHEMBL5996855 | 0.86 | TBXAS1 (0.35) | TSHRLMNANFKB1PMP22TBXAS1 | |
| Ammonia Solution, Strong SCHEMBL10013113 | 0.86 | TSHR (0.33) | TSHRLMNANFKB1PMP22TBXAS1 | |
| SCHEMBL5458895 | 0.86 | LMNA (0.32) | TSHRLMNANFKB1PMP22TBXAS1 | |
| SCHEMBL15911950 | 0.85 | ALDH1A1 (0.33) | TSHRLMNANFKB1PMP22TBXAS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10138379-B2 | N-halamines compounds as multifunctional additives | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2018-11-27 | — | — | US | disclosed |
| US-20150166796-A1 | N-Halamines Compounds as Multifunctional Additives | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM | 2015-06-18 | — | — | US | disclosed |
| EP-1838772-B1 | METHOD FOR TRANSFORMATION OF CONVENTIONAL AND COMMERCIALLY IMPORTANT POLYMERS INTO DURABLE AND RECHARGEABLE ANTIMICROBIAL POLYMERIC MATERIALS | UNIV TEXAS (US) | 2013-11-20 | — | — | EP | disclosed |
| US-7541398-B2 | Method for transformation of conventional and commercially important polymers into durable and rechargeable antimicrobial polymeric materials | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2009-06-02 | — | — | US | disclosed |
| US-20070062884-A1 | N-halamines compounds as multifunctional additives | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2007-03-22 | — | — | US | disclosed |
| US-20060148940-A1 | Method for transformation of conventional and commercially important polymers into durable and rechargeable antimicrobial polymeric materials | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2006-07-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150166796-A1 | N-Halamines Compounds as Multifunctional Additives | NIT2, AAAS, NACA | TSHR 2909/4885LMNA 1646/4885NFKB1 1318/4885 |
| US-10138379-B2 | N-halamines compounds as multifunctional additives | NIT2, AAAS, NACA | TSHR 2909/4885LMNA 1646/4885NFKB1 1318/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.