Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | BCL2 | P10415 | 1/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.39 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | CDC25B | P30305 | 1/20 | 0.39 |
| ▸ | CES1 | P23141 | 1/20 | 0.38 |
| ▸ | PABPC1 | P11940 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
| ▸ | CASP3 | P42574 | 1/20 | 0.37 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.37 |
| ▸ | RELA | Q04206 | 1/20 | 0.37 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.37 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29364188 | 0.82 | MEN1 (0.56) | NPC1RAB9ABCL2MCL1MEN1 | |
| SCHEMBL354514 | 0.82 | MEN1 (0.56) | NPC1RAB9ABCL2MCL1MEN1 | |
| SCHEMBL30130196 | 0.82 | MEN1 (0.56) | NPC1RAB9ABCL2MCL1MEN1 | |
| Ammonia Solution, Strong SCHEMBL28255083 | 0.79 | MEN1 (0.53) | NPC1RAB9ABCL2MCL1MEN1 | |
| SCHEMBL29634145 | 0.79 | MEN1 (0.53) | NPC1RAB9ABCL2MCL1MEN1 | |
| SCHEMBL30458681 | 0.79 | MEN1 (0.53) | NPC1RAB9ABCL2MCL1MEN1 | |
| SCHEMBL16144676 | 0.79 | MEN1 (0.53) | NPC1RAB9ABCL2MCL1MEN1 | |
| SCHEMBL9243671 | 0.79 | NPC1 (0.55) | NPC1RAB9ABCL2MCL1MEN1 | |
| SCHEMBL9737187 | 0.78 | CA12 (0.32) | CES1 | |
| SCHEMBL2516264 | 0.77 | MEN1 (0.50) | NPC1RAB9ABCL2MCL1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5391749-A | Photoinitiators or photosensitizers | CIBA-GEIGY CORPORATION (US) | 1995-02-21 | — | — | US | disclosed |
| US-5338863-A | Catalytic sulfiding | CIBA-GEIGY CORPORATION (US) | 1994-08-16 | — | — | US | disclosed |
| EP-0344109-B1 | Substituted naphthacene-5,12-diones and their use | CIBA GEIGY AG (CH) | 1994-04-27 | — | — | EP | disclosed |
| US-5206390-A | Intermediates for tetrathiotetracenes | CIBA-GEIGY CORPORATION (US) | 1993-04-27 | — | — | US | disclosed |
| EP-0344112-B1 | SUBSTITUTED BISACYLOXYNAPHTHACENES, AND PROCESS FOR THE PREPARATION OF TETRATHIOTETRACENES | CIBA-GEIGY AG (CH) | 1993-01-20 | — | — | EP | disclosed |
| US-5112977-A | Photoinitiators, metallization of polymeric surfaces | CIBA-GEIGY CORPORATION (US) | 1992-05-12 | — | — | US | disclosed |
| US-5011944-A | Substituted α-pyrones | CIBA-GEIGY CORPORATION (US) | 1991-04-30 | — | — | US | disclosed |
| US-4981962-A | CHARGE TRANSFER COMPLEXES | CIBA-GEIGY CORPORATION (US) | 1991-01-01 | — | — | US | disclosed |
| EP-0344113-A2 | Substituted alpha-pyrones and naphthoquinones | CIBA-GEIGY AG (CH) | 1989-11-29 | — | — | EP | disclosed |
| EP-0344112-A2 | Substituted bisacyloxynaphthacenes, and process for the preparation of tetrathiotetracenes | CIBA-GEIGY AG (CH) | 1989-11-29 | — | — | EP | disclosed |
| EP-0344111-A2 | Substituted tetrathio- and tetraselenotetracenes | CIBA-GEIGY AG (CH) | 1989-11-29 | — | — | EP | disclosed |
| EP-0344109-A2 | Substituted naphthacene-5,12-diones and their use | CIBA-GEIGY AG (CH) | 1989-11-29 | — | — | EP | disclosed |