Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | DNM2 | P50570 | 9/20 | 0.40 |
| ▸ | KCNH3 | Q9ULD8 | 2/20 | 0.40 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.38 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.38 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.38 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.38 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28521075 | 1.00 | MAPT (0.47) | MAPTHTTNPSR1KMT2ADNM2 | |
| SCHEMBL10896792 | 1.00 | MAPT (0.47) | MAPTHTTNPSR1KMT2ADNM2 | |
| SCHEMBL8073238 | 0.94 | SLC29A1 (0.43) | MAPTHTTNPSR1KMT2AKCNH3 | |
| SCHEMBL28906134 | 0.79 | CHRNB2 (0.44) | MAPTHTTNPSR1DNM2CHRNB2 | |
| SCHEMBL11364385 | 0.79 | MAPT (0.40) | MAPTCHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL11363805 | 0.79 | MAPT (0.40) | MAPTCHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL4112013 | 0.79 | MAPT (0.40) | MAPTCHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL11359108 | 0.79 | MAPT (0.40) | MAPTCHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL11360058 | 0.79 | MAPT (0.40) | MAPTCHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL11789553 | 0.77 | CYP1A2 (0.61) | MAPTHTTNPSR1KMT2ADNM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3936523-A | CROSSLINKED POLYETHYLENE | SIEMENS AKTIENGESELLSCHAFT (DT) | 1976-02-03 | — | — | US | claimed |
| EP-0483682-B1 | Process for producing plastic foam | MITSUBISHI PETROCHEMICAL CO (JP) | 1995-03-08 | — | — | EP | disclosed |
| US-5216038-A | EPDM crosslinked with homo or copolymers of polyolefins | MITSUBISHI PETROCHEMICAL CO., LTD. (JP) | 1993-06-01 | — | — | US | disclosed |
| EP-0483682-A2 | Process for producing plastic foam | MITSUBISHI PETROCHEMICAL CO., LTD. (JP) | 1992-05-06 | — | — | EP | disclosed |
| US-3936523-A | CROSSLINKED POLYETHYLENE | SIEMENS AKTIENGESELLSCHAFT (DT) | 1976-02-03 | — | — | US | disclosed |