SCHEMBL28906134

SCHEMBL28906134

C=CCOc1ncnc(NCCCC)n1

nearest known ligand 0.44

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
▸ CHRNB2 P17787 2/20 0.44
▸ CHRNB4 P30926 2/20 0.44
▸ CHRNA3 P32297 2/20 0.44
▸ CHRNA4 P43681 2/20 0.44
▸ HRH4 Q9H3N8 1/20 0.36
▸ SLC29A1 Q99808 1/20 0.36
▸ PDCD1 Q15116 1/20 0.35
▸ CD274 Q9NZQ7 1/20 0.35
▸ MAPT P10636 1/20 0.35
▸ HTT P42858 1/20 0.35
▸ NPSR1 Q6W5P4 1/20 0.35
▸ MERTK Q12866 11/20 0.35
▸ FLT3 P36888 10/20 0.35
▸ TYRO3 Q06418 10/20 0.35
▸ GAS6 Q14393 10/20 0.35
▸ AXL P30530 2/20 0.34
▸ DNM2 P50570 2/20 0.33
▸ TLR8 Q9NR97 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8073238 0.85 SLC29A1 (0.43) CHRNB2CHRNB4CHRNA3CHRNA4SLC29A1
SCHEMBL11685193 0.80 CYP1A2 (0.47) HRH4SLC29A1PDCD1CD274MAPT
SCHEMBL28521075 0.79 MAPT (0.47) CHRNB2CHRNB4CHRNA3CHRNA4SLC29A1
SCHEMBL10896792 0.79 MAPT (0.47) CHRNB2CHRNB4CHRNA3CHRNA4SLC29A1
SCHEMBL9243403 0.79 MAPT (0.47) CHRNB2CHRNB4CHRNA3CHRNA4SLC29A1
SCHEMBL8732720 0.74 MAPT (0.44) MAPT
SCHEMBL516082 0.72 KCNH3 (0.54) HRH4MAPTHTTNPSR1DNM2
SCHEMBL31087485 0.70 SLC29A1 (0.42) HRH4SLC29A1MERTKFLT3TYRO3
SCHEMBL6643508 0.70 KMT2A (0.49) HRH4SLC29A1MAPTHTTNPSR1
SCHEMBL10572863 0.70 HRH4 (0.42) HRH4SLC29A1NPSR1MERTKFLT3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112275031-B Preparation method of melt-blown electret polymer filter material 浙江派菲特新材料科技有限公司 2022-05-13 — — CN claimed
CN-112323255-A Oil-smoke-resistant efficient filtering melt-blown fabric and preparation method thereof 浙江派菲特新材料科技有限公司 2021-02-05 — — CN claimed
CN-112275031-A Preparation method of melt-blown electret polymer filter material 浙江派菲特新材料科技有限公司 2021-01-29 — — CN claimed
CN-112251840-A Electret polymer melt-blown fabric and preparation method thereof 宁波德昇医疗科技有限公司 2021-01-22 — — CN claimed
CN-112275031-B Preparation method of melt-blown electret polymer filter material 浙江派菲特新材料科技有限公司 2022-05-13 — — CN disclosed
CN-112323255-A Oil-smoke-resistant efficient filtering melt-blown fabric and preparation method thereof 浙江派菲特新材料科技有限公司 2021-02-05 — — CN disclosed
CN-112275031-A Preparation method of melt-blown electret polymer filter material 浙江派菲特新材料科技有限公司 2021-01-29 — — CN disclosed
CN-112251840-A Electret polymer melt-blown fabric and preparation method thereof 宁波德昇医疗科技有限公司 2021-01-22 — — CN disclosed
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