SCHEMBL9243740

SCHEMBL9243740

C=CC(=O)OC[Si]1(C)CC(C)(CC(C)C)O[Si](C)(C)[Si]1(C)C

nearest known ligand 0.38

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7948196 0.70 TSHR (0.34) TSHR
SCHEMBL3113887 0.63 TSHR (0.33) TSHR
SCHEMBL7519217 0.63 TSHR (0.30) TSHR
SCHEMBL28040562 0.62 TSHR (0.41) TSHR
SCHEMBL1316484 0.61 TSHR (0.47) TSHR
SCHEMBL774725 0.61 TSHR (0.41) TSHR
SCHEMBL2883351 0.61 TSHR (0.47) TSHR
SCHEMBL2884050 0.59 TSHR (0.45) TSHR
SCHEMBL16448 0.58
SCHEMBL28192845 0.58 TSHR (1.00) TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0219312-B1 Improved fluorine containing polymeric compositions useful in contact lenses POLYMER TECHNOLOGY CORP (US) 1995-12-20 EP disclosed
EP-0424099-B1 Method of Preparing Polymeric Compositions for Oxygen Permeable Contact Lenses POLYMER TECHNOLOGY CORP (US) 1995-10-04 EP disclosed
US-5346978-A Polymeric compositions useful in oxygen permeable contact lenses POLYMER TECHNOLOGY CORPORATION (US) 1994-09-13 US disclosed
US-5177168-A Copolymer of an unsaturated carboxylic acid ester POLYMER TECHNOLOGY CORP. (US) 1993-01-05 US disclosed
US-5032658-A Hardness, unsaturated ester POLYMER TECHNOLOGY CORPORATION (US) 1991-07-16 US disclosed
EP-0424099-A2 Method of Preparing Polymeric Compositions for Oxygen Permeable Contact Lenses POLYMER TECHNOLOGY CORPORATION (US) 1991-04-24 EP disclosed
US-4996275-A With silicon group-substituted addition polymers; oxygen permeability, hydrophilic, deposit resistance POLYMER TECHNOLOGY CORPORATION (US) 1991-02-26 US disclosed
US-4686267-A Fluorine containing polymeric compositions useful in contact lenses POLYMER TECHNOLOGY CORPORATION (US) 1987-08-11 US disclosed
EP-0219312-A2 Improved fluorine containing polymeric compositions useful in contact lenses POLYMER TECHNOLOGY CORPORATION (US) 1987-04-22 EP disclosed