Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY14 | Q15391 | 1/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 15/20 | 0.38 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9264776 | 0.91 | ALOX5 (0.36) | P2RY14ALOX5 | |
| SCHEMBL9271610 | 0.91 | ALOX5 (0.39) | P2RY14ALOX5 | |
| SCHEMBL9302999 | 0.90 | ALOX5 (0.42) | P2RY14ALOX5 | |
| SCHEMBL9271846 | 0.87 | ALOX5 (0.44) | P2RY14ALOX5 | |
| SCHEMBL9302868 | 0.84 | ALOX5 (0.42) | P2RY14ALOX5SLC16A3 | |
| SCHEMBL9303431 | 0.84 | ALOX5 (0.42) | P2RY14ALOX5 | |
| SCHEMBL9304055 | 0.83 | ALOX5 (0.43) | P2RY14ALOX5 | |
| SCHEMBL9302885 | 0.83 | ALOX5 (0.37) | P2RY14ALOX5 | |
| SCHEMBL9303146 | 0.82 | ALOX5 (0.42) | P2RY14ALOX5 | |
| SCHEMBL9265197 | 0.82 | ALOX5 (0.42) | P2RY14ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5426109-A | Leukotriene biosynthesis inhibitors; antiinflammatory, cytoprotective agents, antiallergens | MERCK FROSST CANADA, INC. (CA) | 1995-06-20 | — | — | US | disclosed |
| US-5350744-A | Antiinflammatory, antiallergen | MERCK FROSST CANADA, INC. (CA) | 1994-09-27 | — | — | US | disclosed |