1-Methylimidazole

1-Methylimidazole

SCHEMBL9244221

Cn1ccnc1.Cn1ccnc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
NFKB1 P19838 1/20 1.00
QPCT Q16769 1/20 1.00
HSD17B10 Q99714 1/20 1.00
QPCTL Q9NXS2 1/20 1.00
TBXAS1 P24557 3/20 0.42
HTT P42858 1/20 0.36
CYP11B1 P15538 3/20 0.34
CYP11B2 P19099 3/20 0.34
EGLN3 Q9H6Z9 1/20 0.34
PRKCI P41743 1/20 0.34
CYP19A1 P11511 2/20 0.33
CYP3A4 P08684 1/20 0.33
ALDH1A1 P00352 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
1-Methylimidazole SCHEMBL20112 1.00
1-Methylimidazole SCHEMBL4954973 1.00
1-Methylimidazole SCHEMBL17669724 0.97
1-Methylimidazole SCHEMBL4250207 0.97
1-Methylimidazole SCHEMBL556550 0.97
1-Methylimidazole SCHEMBL8045610 0.97 NFKB1 (0.94) NFKB1QPCTHSD17B10QPCTLTBXAS1
1-Methylimidazole SCHEMBL9113015 0.97
1-Methylimidazole SCHEMBL35921 0.97
1-Methylimidazole SCHEMBL20490673 0.97
1-Methylimidazole SCHEMBL5945191 0.97

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2012115936-A2 CATALYSTS FOR POLYURETHANE FOAM POLYOL PREMIXES CONTAINING HALOGENATED OLEFIN BLOWING AGENTS HONEYWELL INTERNATIONAL INC. (US) 2012-08-30 WO disclosed
WO-2012115929-A2 POLYURETHANE FOAM PREMIXES CONTAINING HALOGENATED OLEFIN BLOWING AGENTS AND FOAMS MADE FROM SAME HONEYWELL INTERNATIONAL INC. (US) 2012-08-30 WO disclosed
US-5424393-A Curing into liquid crystals THE DOW CHEMICAL COMPANY (US) 1995-06-13 US disclosed
US-5248740-A Thioepoxides, liquid crystal polymers THE DOW CHEMICAL COMPANY (US) 1993-09-28 US disclosed
US-5182340-A Molding materials having shorter gel time with aliphatic amine curing agents THE DOW CHEMICAL COMPANY (US) 1993-01-26 US disclosed