Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of 1-Methylimidazole. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 1-Methylimidazole SCHEMBL27664516 | 1.00 | NFKB1 (0.94) | — | |
| 1-Methylimidazole SCHEMBL27756040 | 1.00 | — | — | |
| 1-Methylimidazole SCHEMBL9198896 | 1.00 | NFKB1 (0.94) | — | |
| 1-Methylimidazole SCHEMBL29082181 | 0.97 | — | — | |
| 1-Methylimidazole SCHEMBL29205021 | 0.97 | — | — | |
| 1-Methylimidazole SCHEMBL20112 | 0.97 | — | — | |
| 1-Methylimidazole SCHEMBL4954973 | 0.97 | — | — | |
| 1-Methylimidazole SCHEMBL9244221 | 0.97 | NFKB1 (1.00) | — | |
| 1-Methylimidazole SCHEMBL8045610 | 0.94 | NFKB1 (0.94) | — | |
| 1-Methylimidazole SCHEMBL35921 | 0.94 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 433 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119954650-A | Method for synthesizing chain carbonate by metal ion liquid | 中国科学院过程工程研究所 | 2025-05-09 | — | — | CN | claimed |
| EP-4543574-A1 | IONIC LIQUID ENCAPSULATED METAL ORGANIC FRAMEWORK BASED THIN FILM NANOCOMPOSITE MEMBRANE FOR METAL IONS SEPARATION | Commissariat à l'Energie Atomique et aux Energies Alternatives (FR) | 2025-04-30 | — | — | EP | claimed |
| CN-119823090-A | Method for preparing glycolide by catalyzing methyl glycolate through metal-based ionic liquid | 郑州中科新兴产业技术研究院 | 2025-04-15 | — | — | CN | claimed |
| CN-119700885-A | Veterinary traditional Chinese medicine granule for preventing and treating atypical bursa of Fabricius of poultry and application thereof | 石家庄市九洲兽药有限公司 | 2025-03-28 | — | — | CN | claimed |
| CN-114787314-B | Two-component (2K) curable adhesive composition | 汉高股份有限及两合公司 | 2024-11-29 | — | — | CN | claimed |
| CN-118545682-B | Process for preparing potassium perchlorate by emulsion method | 浏阳市化工厂有限公司 | 2024-10-29 | — | — | CN | claimed |
| CN-118754918-A | Ferrocene derivative and preparation method thereof, positive electrode active material and salt-cavity flow battery | 南方科技大学 | 2024-10-11 | — | — | CN | claimed |
| CN-118545682-A | Process for preparing potassium perchlorate by emulsion method | 浏阳市化工厂有限公司 | 2024-08-27 | — | — | CN | claimed |
| CN-118109449-A | Pickering emulsion for synthesizing 1, 3 dioleate-2-palmitic acid triglyceride, preparation method and application | 江苏大学 | 2024-05-31 | — | — | CN | claimed |
| US-20240133117-A1 | DYE RECYCLING METHODS | IMPERIAL COLLEGE INNOVATIONS LIMITED (GB) | 2024-04-25 | — | — | US | claimed |
| CN-101435099-B | Copper plating method | ROHM & HAAS ELECT MAT | 2011-06-08 | — | — | CN | claimed |
| EP-2129663-A2 | MUSCARINIC RECEPTOR ANTAGONISTS | Ranbaxy Laboratories Limited (IN) | 2009-12-09 | — | — | EP | claimed |
| WO-2008104942-A2 | MUSCARINIC RECEPTOR ANTAGONISTS | RANBAXY LABORATORIES LIMITED (IN) | 2008-09-04 | — | — | WO | claimed |
| WO-2008022983-A2 | CONDUCTIVE POLYMER GELS | BASF SE (DE) | 2008-02-28 | — | — | WO | claimed |
| EP-1805266-A1 | CATIONIC AZOAZINIC DYES AND COOLANTS CONTAINING SAID COMPOUNDS | Wella Aktiengesellschaft (DE) | 2007-07-11 | — | — | EP | claimed |
| EP-1663921-B1 | METHOD FOR PRODUCING HALOALKANES FROM ALCOHOLS | BASF AG (DE) | 2007-05-02 | — | — | EP | claimed |
| US-20070055084-A1 | Method for producing haloalkanes from alcohols | BASF AKTIENGESELLSCHAFT (DE) | 2007-03-08 | — | — | US | claimed |
| EP-1663921-A2 | METHOD FOR PRODUCING HALOALKANES FROM ALCOHOLS | BASF AKTIENGESELLSCHAFT (DE) | 2006-06-07 | — | — | EP | claimed |
| WO-2006048057-A1 | CATIONIC AZOAZINIC DYES AND COOLANTS CONTAINING SAID COMPOUNDS | THE PROCTER & GAMBLE COMPANY (US) | 2006-05-11 | — | — | WO | claimed |
| WO-2005026089-A2 | METHOD FOR PRODUCING HALOALKANES FROM ALCOHOLS | BASF AKTIENGESELLSCHAFT (DE) | 2005-03-24 | — | — | WO | claimed |