SCHEMBL9244302

SCHEMBL9244302

O=C(Cl)c1ccccc1Oc1ccccc1Oc1ccccc1

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CTNNB1 P35222 1/20 0.62
HTT P42858 3/20 0.51
SMN1; SMN2 Q16637 1/20 0.51
ALDH1A1 P00352 5/20 0.49
L3MBTL1 Q9Y468 4/20 0.49
TDP1 Q9NUW8 2/20 0.49
MAPK8 P45983 1/20 0.49
GAA P10253 1/20 0.49
HPGD P15428 1/20 0.49
ATM Q13315 1/20 0.49
RAB9A P51151 1/20 0.49
MEN1 O00255 3/20 0.48
KMT2A Q03164 3/20 0.48
LMNA P02545 2/20 0.48
MAPT P10636 2/20 0.48
HSD17B10 Q99714 2/20 0.48
TSHR P16473 2/20 0.48
NPSR1 Q6W5P4 1/20 0.48
TP53 P04637 1/20 0.48
MAPK1 P28482 2/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL645199 0.96 CTNNB1 (0.67) CTNNB1HTTSMN1; SMN2ALDH1A1L3MBTL1
SCHEMBL9243804 0.93 CTNNB1 (0.62) CTNNB1HTTSMN1; SMN2ALDH1A1L3MBTL1
SCHEMBL3357655 0.88 ALDH1A1 (0.52) CTNNB1HTTSMN1; SMN2ALDH1A1TDP1
SCHEMBL9325745 0.86 CTNNB1 (0.54) CTNNB1HTTSMN1; SMN2ALDH1A1L3MBTL1
SCHEMBL1537710 0.85 HTT (0.70) CTNNB1HTTSMN1; SMN2ALDH1A1L3MBTL1
SCHEMBL9646975 0.85 CTNNB1 (0.67) CTNNB1HTTSMN1; SMN2ALDH1A1L3MBTL1
SCHEMBL1683907 0.82 CTNNB1 (0.54) CTNNB1HTTSMN1; SMN2ALDH1A1L3MBTL1
SCHEMBL9244300 0.82 CTNNB1 (0.54) CTNNB1HTTSMN1; SMN2ALDH1A1L3MBTL1
SCHEMBL923513 0.81 CTNNB1 (0.53) CTNNB1HTTSMN1; SMN2ALDH1A1L3MBTL1
SCHEMBL1798 0.80 CTNNB1 (0.71) CTNNB1HTTSMN1; SMN2ALDH1A1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0368006-B1 Copolymers containing polybenzoxazole polybenzothiazole and polybenzimidazole moieties DOW CHEMICAL CO (US) 1995-04-05 EP disclosed
US-5151489-A Block copolymers for compression molding to form fibers, films and laminates THE DOW CHEMICAL COMPANY (US) 1992-09-29 US disclosed
US-5110894-A Thermoplastic films and fibers of high strength and thermal stability THE DOW CHEMICAL COMPANY (US) 1992-05-05 US disclosed
US-5098985-A Block copolymers for films, fibers, laminates or compression moldings THE DOW CHEMICAL COMPANY (US) 1992-03-24 US disclosed
EP-0392008-A4 COPOLYMERS CONTAINING POLYBENZOXAZOLE, POLYBENZOTHIAZOLE AND POLYBENZIMIDAZOLE MOIETIES 1991-09-04 EP disclosed
EP-0392008-A1 COPOLYMERS CONTAINING POLYBENZOXAZOLE, POLYBENZOTHIAZOLE AND POLYBENZIMIDAZOLE MOIETIES THE DOW CHEMICAL COMPANY (US) 1990-10-17 EP disclosed
EP-0368006-A2 Copolymers containing polybenzoxazole polybenzothiazole and polybenzimidazole moieties THE DOW CHEMICAL COMPANY (US) 1990-05-16 EP disclosed
WO-1990003995-A1 COPOLYMERS CONTAINING POLYBENZOXAZOLE, POLYBENZOTHIAZOLE AND POLYBENZIMIDAZOLE MOIETIES THE DOW CHEMICAL COMPANY (US) 1990-04-19 WO disclosed
EP-0173408-B1 PREPARING POLY(ARYLENE KETONES) RAYCHEM CORPORATION (a Delaware corporation) (US) 1989-07-26 EP disclosed
US-4693851-A ADDING ACID CATALYST, HEATING, DISTILLING RAYCHEM CORPORATION (US) 1987-09-15 US disclosed
US-4665151-A Preparing poly (arylene ketone) with liquefaction agent treatment RAYCHEM CORPORATION (US) 1987-05-12 US disclosed
EP-0173408-A2 Preparing poly(arylene ketones) RAYCHEM CORPORATION (a Delaware corporation) (US) 1986-03-05 EP disclosed