Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | BCHE | P06276 | 5/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.37 |
| ▸ | ACHE | P22303 | 2/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.36 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1138460 | 0.87 | TSHR (0.55) | KMT2ATSHRLMNABCHEALDH1A1 | |
| SCHEMBL1939153 | 0.82 | KMT2A (0.71) | KMT2AGAAMEN1TSHRLMNA | |
| SCHEMBL7029903 | 0.80 | KMT2A (0.48) | KMT2AGAAMEN1TSHRLMNA | |
| SCHEMBL1138704 | 0.78 | TSHR (0.71) | KMT2AGAAMEN1TSHRLMNA | |
| SCHEMBL698553 | 0.78 | KMT2A (0.47) | KMT2AGAAMEN1TSHRLMNA | |
| SCHEMBL7470898 | 0.77 | GAA (0.46) | KMT2AGAAMEN1TSHRLMNA | |
| SCHEMBL7642945 | 0.76 | TSHR (0.73) | KMT2AGAAMEN1TSHRLMNA | |
| SCHEMBL1948723 | 0.76 | TSHR (0.53) | KMT2AGAAMEN1TSHRALDH1A1 | |
| SCHEMBL7473740 | 0.76 | KMT2A (0.45) | KMT2AGAAMEN1TSHRLMNA | |
| SCHEMBL27839363 | 0.76 | TSHR (0.48) | KMT2AGAAMEN1TSHRLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0467849-B1 | Stabilized monomer compositions | CIBA GEIGY AG (CH) | 1995-04-05 | — | — | EP | claimed |
| US-5300647-A | Light stabilizers for polyolefins, other polymers | CIBA-GEIGY CORPORATION (US) | 1994-04-05 | — | — | US | claimed |
| EP-0467849-A1 | Stabilized monomer compositions | CIBA-GEIGY AG (CH) | 1992-01-22 | — | — | EP | claimed |
| EP-0467849-B1 | Stabilized monomer compositions | CIBA GEIGY AG (CH) | 1995-04-05 | — | — | EP | disclosed |
| US-5300647-A | Light stabilizers for polyolefins, other polymers | CIBA-GEIGY CORPORATION (US) | 1994-04-05 | — | — | US | disclosed |
| EP-0309400-B1 | N-acyloxy hindered amine stabilizers | CIBA GEIGY AG (CH) | 1994-03-02 | — | — | EP | disclosed |
| EP-0309400-A2 | N-acyloxy hindered amine stabilizers | CIBA-GEIGY AG (CH) | 1989-03-29 | — | — | EP | disclosed |