Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1046024 | 0.91 | TSHR (0.44) | TSHRALDH1A1THRB | |
| SCHEMBL332509 | 0.87 | TSHR (0.47) | TSHRALDH1A1THRB | |
| SCHEMBL1274402 | 0.86 | TSHR (0.40) | TSHRALDH1A1THRB | |
| SCHEMBL19499569 | 0.86 | TSHR (0.40) | TSHRALDH1A1THRB | |
| SCHEMBL9714988 | 0.84 | TSHR (0.43) | TSHRALDH1A1THRB | |
| SCHEMBL9915559 | 0.83 | TSHR (0.44) | TSHRALDH1A1THRB | |
| SCHEMBL11156160 | 0.80 | TSHR (0.36) | TSHRALDH1A1THRB | |
| SCHEMBL18719914 | 0.80 | TSHR (0.47) | TSHRALDH1A1THRB | |
| SCHEMBL14616384 | 0.80 | TSHR (0.41) | TSHRALDH1A1THRB | |
| SCHEMBL19499562 | 0.80 | THRB (0.43) | TSHRALDH1A1THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0219312-B1 | Improved fluorine containing polymeric compositions useful in contact lenses | POLYMER TECHNOLOGY CORP (US) | 1995-12-20 | — | — | EP | disclosed |
| EP-0424099-B1 | Method of Preparing Polymeric Compositions for Oxygen Permeable Contact Lenses | POLYMER TECHNOLOGY CORP (US) | 1995-10-04 | — | — | EP | disclosed |
| US-5346978-A | Polymeric compositions useful in oxygen permeable contact lenses | POLYMER TECHNOLOGY CORPORATION (US) | 1994-09-13 | — | — | US | disclosed |
| US-5177168-A | Copolymer of an unsaturated carboxylic acid ester | POLYMER TECHNOLOGY CORP. (US) | 1993-01-05 | — | — | US | disclosed |
| US-5032658-A | Hardness, unsaturated ester | POLYMER TECHNOLOGY CORPORATION (US) | 1991-07-16 | — | — | US | disclosed |
| EP-0424099-A2 | Method of Preparing Polymeric Compositions for Oxygen Permeable Contact Lenses | POLYMER TECHNOLOGY CORPORATION (US) | 1991-04-24 | — | — | EP | disclosed |
| US-4996275-A | With silicon group-substituted addition polymers; oxygen permeability, hydrophilic, deposit resistance | POLYMER TECHNOLOGY CORPORATION (US) | 1991-02-26 | — | — | US | disclosed |
| US-4686267-A | Fluorine containing polymeric compositions useful in contact lenses | POLYMER TECHNOLOGY CORPORATION (US) | 1987-08-11 | — | — | US | disclosed |
| EP-0219312-A2 | Improved fluorine containing polymeric compositions useful in contact lenses | POLYMER TECHNOLOGY CORPORATION (US) | 1987-04-22 | — | — | EP | disclosed |