SCHEMBL14616384

SCHEMBL14616384

B[Si](B)(B)O[Si](C)(C)COC(=O)C(=C)C

nearest known ligand 0.41

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.41
ALDH1A1 P00352 2/20 0.41
THRB P10828 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL332509 0.88 TSHR (0.47) TSHRALDH1A1THRB
SCHEMBL1046024 0.85 TSHR (0.44) TSHRALDH1A1THRB
SCHEMBL9915559 0.85 TSHR (0.44) TSHRALDH1A1THRB
SCHEMBL19499562 0.81 THRB (0.43) TSHRALDH1A1THRB
SCHEMBL7190871 0.80 TSHR (0.47) TSHRALDH1A1THRB
SCHEMBL19499569 0.80 TSHR (0.40) TSHRALDH1A1THRB
SCHEMBL9244658 0.80 TSHR (0.40) TSHRALDH1A1THRB
SCHEMBL1274402 0.80 TSHR (0.40) TSHRALDH1A1THRB
SCHEMBL10946327 0.79 TSHR (0.39) TSHRALDH1A1THRB
SCHEMBL13852315 0.79 THRB (0.41) TSHRALDH1A1THRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9897729-B2 Photosensitive resin composition for color filter and application thereof CHI MEI CORPORATION (TW) 2018-02-20 US disclosed
US-9851638-B2 Photosensitive polysiloxane composition and uses thereof CHI MEI CORPORATION (TW) 2017-12-26 US disclosed
US-20170121441-A1 POLYMER, COMPOSITION, OPTICAL FILM, AND LIQUID CRYSTAL DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2017-05-04 US disclosed
US-20150315376-A1 PHOTOSENSITIVE RESIN COMPOSITION FOR COLOR FILTER AND APPLICATION THEREOF CHI MEI CORPORATION (TW) 2015-11-05 US disclosed
US-20150031808-A1 PHOTOSENSITIVE POLYSILOXANE COMPOSITION AND USES THEREOF CHI MEI CORPORATION (TW) 2015-01-29 US disclosed
US-20140171544-A1 CONTACT LENS SAUFLON CL LIMITED (GB) 2014-06-19 US disclosed
US-8703891-B2 Contact lens SAUFLON CL LIMITED (GB) 2014-04-22 US disclosed
US-20130015595-A1 CONTACT LENS SAUFLON CL LIMITED (GB) 2013-01-17 US disclosed