Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.40 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.40 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.40 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.40 |
| ▸ | HRH1 | P35367 | 1/20 | 0.40 |
| ▸ | DGAT1 | O75907 | 7/20 | 0.39 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.39 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
| ▸ | P2RY14 | Q15391 | 4/20 | 0.38 |
| ▸ | GABRP | O00591 | 1/20 | 0.37 |
| ▸ | GABRD | O14764 | 1/20 | 0.37 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.37 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.37 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.37 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9244763 | 1.00 | NPC1 (0.50) | NPC1RAB9ACSNK2A2CSNK2A1ADRA2A | |
| Hydrochloric Acid SCHEMBL9408018 | 0.99 | NPC1 (0.49) | NPC1RAB9ACSNK2A2CSNK2A1ADRA2A | |
| Hydrochloric Acid SCHEMBL9407956 | 0.99 | NPC1 (0.49) | NPC1RAB9ACSNK2A2CSNK2A1ADRA2A | |
| SCHEMBL9407972 | 0.86 | DGAT1 (0.41) | NPC1RAB9ACSNK2A2CSNK2A1ADRA2A | |
| SCHEMBL9407975 | 0.86 | DGAT1 (0.41) | NPC1RAB9ACSNK2A2CSNK2A1ADRA2A | |
| Hydrochloric Acid SCHEMBL9408043 | 0.85 | DGAT1 (0.41) | NPC1RAB9ACSNK2A2CSNK2A1ADRA2A | |
| Hydrochloric Acid SCHEMBL9408112 | 0.85 | DGAT1 (0.41) | NPC1RAB9ACSNK2A2CSNK2A1ADRA2A | |
| SCHEMBL9408121 | 0.84 | DGAT1 (0.38) | RAB9ADGAT1P2RY14GSK3BDYRK1A | |
| SCHEMBL9408125 | 0.84 | DGAT1 (0.38) | RAB9ADGAT1P2RY14GSK3BDYRK1A | |
| SCHEMBL13098792 | 0.84 | NPC1 (0.48) | NPC1RAB9ACSNK2A2CSNK2A1DGAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0608858-A1 | 5-Membered heterocycles as aggregation inhibitors | Dr. Karl Thomae GmbH (DE) | 1994-08-03 | — | — | EP | claimed |
| JP-7002851-A | — | — | None | — | — | JP | disclosed |
| JP-H072851-A | FIVE-MEMBERED HETEROCYCLIC COMPOUND, ITS PREPARATION AND PHARMACEUTICAL CONTAINING IT | DR KARL THOMAE GMBH | 1995-01-06 | — | — | JP | disclosed |
| EP-0608858-A1 | 5-Membered heterocycles as aggregation inhibitors | Dr. Karl Thomae GmbH (DE) | 1994-08-03 | — | — | EP | disclosed |