Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 5/20 | 0.41 |
| ▸ | GSK3B | P49841 | 1/20 | 0.38 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.38 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.37 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.37 |
| ▸ | PARP1 | P09874 | 1/20 | 0.36 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.36 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.36 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.36 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.36 |
| ▸ | HRH1 | P35367 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | P2RY14 | Q15391 | 2/20 | 0.35 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.35 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.35 |
| ▸ | USP25 | Q9UHP3 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9407975 | 1.00 | DGAT1 (0.41) | DGAT1GSK3BDYRK1ACSNK2A2CSNK2A1 | |
| Hydrochloric Acid SCHEMBL9408112 | 0.99 | DGAT1 (0.41) | DGAT1GSK3BDYRK1ACSNK2A2CSNK2A1 | |
| Hydrochloric Acid SCHEMBL9408043 | 0.99 | DGAT1 (0.41) | DGAT1GSK3BDYRK1ACSNK2A2CSNK2A1 | |
| SCHEMBL9408125 | 0.89 | DGAT1 (0.38) | DGAT1GSK3BDYRK1AALDH1A1RAB9A | |
| SCHEMBL9408121 | 0.89 | DGAT1 (0.38) | DGAT1GSK3BDYRK1AALDH1A1RAB9A | |
| Hydrochloric Acid SCHEMBL9407959 | 0.88 | MAPT (0.38) | DGAT1GSK3BDYRK1AALDH1A1RAB9A | |
| Hydrochloric Acid SCHEMBL9408026 | 0.88 | DGAT1 (0.35) | DGAT1GSK3BDYRK1ACSNK2A2CSNK2A1 | |
| SCHEMBL9244763 | 0.86 | NPC1 (0.50) | DGAT1GSK3BDYRK1ACSNK2A2CSNK2A1 | |
| SCHEMBL9244757 | 0.86 | NPC1 (0.50) | DGAT1GSK3BDYRK1ACSNK2A2CSNK2A1 | |
| SCHEMBL9408053 | 0.86 | NR1H4 (0.39) | DGAT1GSK3BDYRK1ACSNK2A2CSNK2A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0608858-A1 | 5-Membered heterocycles as aggregation inhibitors | Dr. Karl Thomae GmbH (DE) | 1994-08-03 | — | — | EP | claimed |
| EP-0608858-A1 | 5-Membered heterocycles as aggregation inhibitors | Dr. Karl Thomae GmbH (DE) | 1994-08-03 | — | — | EP | disclosed |