Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.57 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.57 |
| ▸ | SRC | P12931 | 1/20 | 0.57 |
| ▸ | HPGD | P15428 | 1/20 | 0.57 |
| ▸ | CASP1 | P29466 | 1/20 | 0.57 |
| ▸ | CASP7 | P55210 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | ATM | Q13315 | 1/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.57 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.57 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.53 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23640376 | 0.76 | KDM4E (0.57) | KDM4EHSD17B10HSD17B3MEN1ALDH1A1 | |
| SCHEMBL600311 | 0.76 | KDM4E (0.58) | KDM4EHSD17B10HSD17B3ALDH1A1GAA | |
| SCHEMBL15842662 | 0.74 | HSD17B3 (0.69) | KDM4EHSD17B10HSD17B3MEN1ALDH1A1 | |
| SCHEMBL28145934 | 0.74 | MAOA (0.54) | KDM4EHSD17B10ALDH1A1HPGDKMT2A | |
| SCHEMBL9361777 | 0.74 | ALDH1A1 (0.56) | KDM4EHSD17B10HSD17B3MEN1ALDH1A1 | |
| SCHEMBL698688 | 0.74 | ALDH1A1 (0.63) | KDM4EHSD17B10HSD17B3MEN1ALDH1A1 | |
| SCHEMBL30177134 | 0.74 | ALDH1A1 (0.63) | KDM4EHSD17B10HSD17B3MEN1ALDH1A1 | |
| SCHEMBL7914365 | 0.73 | HSD17B3 (0.67) | KDM4EHSD17B10HSD17B3MEN1ALDH1A1 | |
| SCHEMBL7813420 | 0.73 | HSD17B3 (0.67) | KDM4EHSD17B10HSD17B3MEN1ALDH1A1 | |
| SCHEMBL307508 | 0.73 | HSD17B3 (1.00) | KDM4EHSD17B10HSD17B3MEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5473083-A | Skin disorders, cancer, Aids | LEHIGH UNIVERSITY (US) | 1995-12-05 | — | — | US | disclosed |
| US-5356929-A | Skin, blood and bone marrow disorders | LEHIGH UNIVERSITY (US) | 1994-10-18 | — | — | US | disclosed |