SCHEMBL9245458

SCHEMBL9245458

C=C(CCC)C(=O)OC(=O)C(=O)O

nearest known ligand 0.41

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.41
FFAR3 O14843 4/20 0.39
HDAC3 O15379 4/20 0.39
HDAC1 Q13547 4/20 0.39
HDAC2 Q92769 4/20 0.39
HDAC8 Q9BY41 4/20 0.39
CES2 O00748 1/20 0.35
CES1 P23141 1/20 0.35
TSHR P16473 3/20 0.32
AKR1B1 P15121 1/20 0.30
HDAC6 Q9UBN7 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10527328 0.86 ALDH1A1 (0.44) ALDH1A1FFAR3HDAC3HDAC1HDAC2
SCHEMBL629110 0.84 ALDH1A1 (0.42) ALDH1A1FFAR3HDAC3HDAC1HDAC2
SCHEMBL3862259 0.83 CES1 (0.42) ALDH1A1FFAR3HDAC3HDAC1HDAC2
Acetic Acid SCHEMBL27838110 0.81 HSD17B10 (0.41) ALDH1A1FFAR3HDAC3HDAC1HDAC2
SCHEMBL8360661 0.80 HSD17B10 (0.44) ALDH1A1FFAR3HDAC3HDAC1HDAC2
SCHEMBL6896365 0.78 ALDH1A1 (0.41) ALDH1A1FFAR3HDAC3HDAC1HDAC2
Water SCHEMBL27348784 0.78 HSD17B10 (0.42) ALDH1A1FFAR3HDAC3HDAC1HDAC2
SCHEMBL8344030 0.78 ALDH1A1 (0.37) ALDH1A1FFAR3HDAC3HDAC1HDAC2
SCHEMBL6916133 0.77 CES1 (0.46) ALDH1A1CES2CES1TSHRAKR1B1
SCHEMBL7197360 0.77 ALDH1A1 (0.44) ALDH1A1FFAR3HDAC3HDAC1HDAC2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5442096-A Compound contains a alpha-ketoester and a polymerizable double bond NIPPON PAINT CO., LTD. (JP) 1995-08-15 US disclosed
EP-0621258-A1 Polymerisable compound and polymer therefrom Nippon Paint Co., Ltd. (JP) 1994-10-26 EP disclosed
US-5248749-A Adhesives and coatings NIPPON PAINT CO., LTD. (JP) 1993-09-28 US disclosed
US-5169896-A Curable mixture of compound having at least two hydroxyl group and homo- or copolymer with alpha-ketoester group and double bond; esterification; coatings, adhesives, plastics NIPPON PAINT CO., LTD. (JP) 1992-12-08 US disclosed
US-5117044-A Unsaturated ester NIPPON PAINT CO., LTD. (JP) 1992-05-26 US disclosed
EP-0378429-A2 Polymerisable compound and polymer therefrom NIPPON PAINT CO., LTD. (JP) 1990-07-18 EP disclosed