Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDGFRB | P09619 | 2/20 | 0.32 |
| ▸ | PDGFRA | P16234 | 2/20 | 0.32 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.31 |
| ▸ | CHRNA2 | Q15822 | 2/20 | 0.31 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.31 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.31 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.31 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.31 |
| ▸ | BACE1 | P56817 | 1/20 | 0.30 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9245762 | 1.00 | PDGFRB (0.32) | PDGFRBPDGFRACHRNB2CHRNA2CHRNB4 | |
| SCHEMBL9245757 | 1.00 | PDGFRB (0.32) | PDGFRBPDGFRACHRNB2CHRNA2CHRNB4 | |
| SCHEMBL9245767 | 1.00 | PDGFRB (0.32) | PDGFRBPDGFRACHRNB2CHRNA2CHRNB4 | |
| SCHEMBL9249549 | 0.90 | PDGFRB (0.31) | PDGFRBPDGFRA | |
| SCHEMBL9249573 | 0.90 | PDGFRB (0.31) | PDGFRBPDGFRA | |
| SCHEMBL9249568 | 0.90 | PDGFRB (0.31) | PDGFRBPDGFRA | |
| SCHEMBL9249562 | 0.90 | PDGFRB (0.31) | PDGFRBPDGFRA | |
| SCHEMBL9247692 | 0.88 | CHRNB2 (0.32) | PDGFRBPDGFRACHRNB2CHRNA2CHRNB4 | |
| SCHEMBL9247696 | 0.88 | CHRNB2 (0.32) | PDGFRBPDGFRACHRNB2CHRNA2CHRNB4 | |
| SCHEMBL9247682 | 0.88 | CHRNB2 (0.32) | PDGFRBPDGFRACHRNB2CHRNA2CHRNB4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5447657-A | Liquid crystal compounds | HOFFMANN-LA ROCHE INC. (US) | 1995-09-05 | — | — | US | disclosed |