Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 2/20 | 0.32 |
| ▸ | CHRNA2 | Q15822 | 2/20 | 0.32 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.32 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.32 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.32 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.31 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.31 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.31 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9247692 | 1.00 | CHRNB2 (0.32) | CHRNB2CHRNA2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL9247682 | 1.00 | CHRNB2 (0.32) | CHRNB2CHRNA2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL9246405 | 0.91 | CYP11B1 (0.32) | CHRNB2CHRNA2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL9246411 | 0.91 | CYP11B1 (0.32) | CHRNB2CHRNA2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL9246379 | 0.91 | CYP11B1 (0.32) | CHRNB2CHRNA2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL9247857 | 0.88 | GRM5 (0.32) | CHRNB2CHRNA2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL9247865 | 0.88 | GRM5 (0.32) | CHRNB2CHRNA2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL9247871 | 0.88 | GRM5 (0.32) | CHRNB2CHRNA2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL9245767 | 0.88 | PDGFRB (0.32) | CHRNB2CHRNA2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL9245772 | 0.88 | PDGFRB (0.32) | CHRNB2CHRNA2CHRNB4CHRNA3CHRNA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5447657-A | Liquid crystal compounds | HOFFMANN-LA ROCHE INC. (US) | 1995-09-05 | — | — | US | disclosed |