Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | ESR1 | P03372 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.32 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.32 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9279074 | 0.74 | MAPK1 (0.46) | ESR2ALDH1A1ESR1CYP3A4ALOX15 | |
| SCHEMBL9858404 | 0.74 | CYP2D6 (0.38) | ESR2ALDH1A1ESR1CYP3A4ALOX15 | |
| SCHEMBL4352236 | 0.72 | MAPK1 (0.44) | ESR2ALDH1A1ESR1CYP3A4ALOX15 | |
| SCHEMBL2429063 | 0.72 | ALDH1A1 (0.46) | ESR2ALDH1A1ESR1CYP3A4ALOX15 | |
| SCHEMBL28531948 | 0.71 | SLC6A4 (0.42) | ESR2ALDH1A1ESR1CYP3A4ALOX15 | |
| Ammonia Solution, Strong SCHEMBL28224949 | 0.70 | ALDH1A1 (0.44) | ESR2ALDH1A1ESR1CYP3A4ALOX15 | |
| SCHEMBL575235 | 0.69 | MAPK1 (0.46) | ESR2ALDH1A1ESR1CYP3A4ALOX15 | |
| SCHEMBL9252948 | 0.69 | CYP2D6 (0.39) | ESR2ALDH1A1ESR1CYP3A4ALOX15 | |
| SCHEMBL1538376 | 0.69 | RIPK1 (0.42) | ESR2ALDH1A1ESR1CYP3A4ALOX15 | |
| SCHEMBL11133348 | 0.69 | ALDH1A1 (0.43) | ESR2ALDH1A1ESR1CYP3A4ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0399284-B1 | Method for the production of geminal diarylalkanes, geminal diarylalkanes and alk(en)ylated aromatic compounds | BAYER AG (DE) | 1995-08-02 | — | — | EP | disclosed |
| US-5136114-A | PROCESS FOR THE PREPARATION OF GEMINAL DIARYLALKANES, NEW GEMINAL DIARYLALKANES AND ALK(EN)YLATED AROMATIC COMPOUNDS | BAYER AKTIENGESELLSCHAFT (DE) | 1992-08-04 | — | — | US | disclosed |
| EP-0399284-A2 | Method for the production of geminal diarylalkanes, geminal diarylalkanes and alk(en)ylated aromatic compounds | BAYER AG (DE) | 1990-11-28 | — | — | EP | disclosed |