Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDIA6 | Q15084 | 1/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | PTGES2 | Q9H7Z7 | 5/20 | 0.35 |
| ▸ | CA12 | O43570 | 2/20 | 0.35 |
| ▸ | CA1 | P00915 | 2/20 | 0.35 |
| ▸ | CA2 | P00918 | 2/20 | 0.35 |
| ▸ | CA9 | Q16790 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28182063 | 0.80 | CA2 (0.45) | PDIA6TAAR1ALDH1A1KDM4EMEN1 | |
| SCHEMBL23300824 | 0.79 | CA2 (0.48) | PDIA6ALDH1A1KDM4EPTGES2CA12 | |
| SCHEMBL20478175 | 0.79 | PDIA6 (0.40) | PDIA6TAAR1ALDH1A1KDM4EMEN1 | |
| SCHEMBL10431753 | 0.79 | PDIA6 (0.43) | PDIA6TAAR1ALDH1A1KDM4EMEN1 | |
| SCHEMBL28605818 | 0.78 | CA2 (0.45) | PDIA6ALDH1A1KDM4EMEN1POLB | |
| SCHEMBL28906302 | 0.78 | CA2 (0.45) | PDIA6ALDH1A1KDM4EMEN1POLB | |
| SCHEMBL28906315 | 0.78 | CA2 (0.45) | PDIA6ALDH1A1KDM4EMEN1POLB | |
| SCHEMBL12497682 | 0.78 | CA2 (0.45) | PDIA6ALDH1A1KDM4EMEN1POLB | |
| SCHEMBL1806651 | 0.77 | KDM4E (0.41) | PDIA6TAAR1ALDH1A1KDM4EMEN1 | |
| SCHEMBL8215092 | 0.77 | CA2 (0.42) | PDIA6TAAR1ALDH1A1KDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0473673-A4 | METHOD FOR PROTECTION FROM AZT SIDE EFFECTS AND TOXICITY | US BIOSCIENCE (US) | 1995-05-17 | — | — | EP | disclosed |
| EP-0473673-A1 | METHOD FOR PROTECTION FROM AZT SIDE EFFECTS AND TOXICITY | U.S. BIOSCIENCE (US) | 1992-03-11 | — | — | EP | disclosed |
| WO-1990014007-A1 | METHOD FOR PROTECTION FROM AZT SIDE EFFECTS AND TOXICITY | U.S. BIOSCIENCE (US) | 1990-11-29 | — | — | WO | disclosed |