Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A2 | P31213 | 2/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | NR1H4 | Q96RI1 | 3/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA3 | P07451 | 1/20 | 0.46 |
| ▸ | TYR | P14679 | 1/20 | 0.46 |
| ▸ | DRD1 | P21728 | 1/20 | 0.46 |
| ▸ | CA4 | P22748 | 1/20 | 0.46 |
| ▸ | CA6 | P23280 | 1/20 | 0.46 |
| ▸ | CA5A | P35218 | 1/20 | 0.46 |
| ▸ | CA7 | P43166 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzoic Acid SCHEMBL20874404 | 0.92 | SMN1; SMN2 (0.57) | SRD5A2TSHRSMN1; SMN2CYP2C9CA12 | |
| SCHEMBL3137092 | 0.86 | SMN1; SMN2 (0.62) | SMN1; SMN2CYP2C9ALDH1A1GAACA12 | |
| SCHEMBL8167142 | 0.84 | ALDH1A1 (0.69) | SMN1; SMN2ALDH1A1GAAMAPTHDAC1 | |
| SCHEMBL7038963 | 0.82 | POLB (0.68) | SMN1; SMN2CYP2C9ALDH1A1GAAPOLB | |
| 4-Nitrobenzoic Acid SCHEMBL10447540 | 0.82 | TDP1 (0.57) | SRD5A2TP53SMN1; SMN2GAAPOLB | |
| SCHEMBL11705058 | 0.80 | TSHR (0.67) | SRD5A2TP53TSHRSMN1; SMN2ALDH1A1 | |
| SCHEMBL24590217 | 0.79 | MAPT (0.70) | TP53SMN1; SMN2ALDH1A1GAACA1 | |
| SCHEMBL7038117 | 0.79 | ALDH1A1 (0.60) | SMN1; SMN2ALDH1A1GAAPOLBLMNA | |
| SCHEMBL3716265 | 0.79 | SRD5A2 (0.53) | SRD5A2TP53TSHRNR1H4EPHX2 | |
| SCHEMBL9244497 | 0.78 | EPHX2 (0.52) | NR1H4EPHX2ALDH1A1GAACA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5424333-A | Anthelmintic N'-substituted-N,N'-disubstitutedhydrazines | ROHM AND HAAS COMPANY (US) | 1995-06-13 | — | — | US | disclosed |
| US-5117057-A | Insecticidal N' substituted-N-N'-disubstituted-hydrazines | ROHM AND HAAS COMPANY (US) | 1992-05-26 | — | — | US | disclosed |