Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.69 |
| ▸ | GAA | P10253 | 2/20 | 0.69 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.55 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.53 |
| ▸ | RAB9A | P51151 | 7/20 | 0.52 |
| ▸ | NPC1 | O15118 | 6/20 | 0.52 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | CCR6 | P51684 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9247147 | 0.84 | SRD5A2 (0.50) | ALDH1A1GAAHDAC1RAB9ANPC1 | |
| SCHEMBL7103221 | 0.83 | ALDH1A1 (1.00) | ALDH1A1GAAHDAC1HDAC6TDP1 | |
| SCHEMBL7038963 | 0.82 | POLB (0.68) | ALDH1A1GAAHDAC1TDP1RAB9A | |
| SCHEMBL3137092 | 0.82 | SMN1; SMN2 (0.62) | ALDH1A1GAAHDAC1HDAC6RAB9A | |
| SCHEMBL8173747 | 0.80 | ALDH1A1 (0.58) | ALDH1A1GAAHDAC1HDAC6TDP1 | |
| Toluene SCHEMBL8172415 | 0.80 | SMN1; SMN2 (0.51) | ALDH1A1GAATDP1RAB9ANPC1 | |
| SCHEMBL1526586 | 0.80 | CYP2C19 (0.45) | ALDH1A1GAASMN1; SMN2KDM4E | |
| SCHEMBL24590217 | 0.79 | MAPT (0.70) | ALDH1A1GAAHDAC1TDP1RAB9A | |
| SCHEMBL7038117 | 0.79 | ALDH1A1 (0.60) | ALDH1A1GAATDP1RAB9ANPC1 | |
| SCHEMBL2264435 | 0.79 | ALDH1A1 (0.61) | ALDH1A1GAAHDAC1HDAC6RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170174619-A1 | HDAC INHIBITOR COMPOUNDS AND METHODS OF TREATMENT | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. | 2017-06-22 | — | — | US | claimed |
| WO-2015153516-A1 | HDAC INHIBITOR COMPOUNDS AND METHODS OF TREATMENT | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION (US) | 2015-10-08 | — | — | WO | claimed |
| US-11731934-B2 | HDAC inhibitor compounds and methods of treatment | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2023-08-22 | — | — | US | disclosed |
| US-11731934-B2 | HDAC inhibitor compounds and methods of treatment | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2023-08-22 | — | — | US | disclosed |
| US-20210009509-A1 | HDAC INHIBITOR COMPOUNDS AND METHODS OF TREATMENT | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. | 2021-01-14 | — | — | US | disclosed |
| US-20210009509-A1 | HDAC INHIBITOR COMPOUNDS AND METHODS OF TREATMENT | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. | 2021-01-14 | — | — | US | disclosed |
| US-10807944-B2 | HDAC inhibitor compounds and methods of treatment | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2020-10-20 | — | — | US | disclosed |
| US-10807944-B2 | HDAC inhibitor compounds and methods of treatment | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2020-10-20 | — | — | US | disclosed |
| US-20170174619-A1 | HDAC INHIBITOR COMPOUNDS AND METHODS OF TREATMENT | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. | 2017-06-22 | — | — | US | disclosed |
| US-20170174619-A1 | HDAC INHIBITOR COMPOUNDS AND METHODS OF TREATMENT | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. | 2017-06-22 | — | — | US | disclosed |
| WO-2015153516-A1 | HDAC INHIBITOR COMPOUNDS AND METHODS OF TREATMENT | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION (US) | 2015-10-08 | — | — | WO | disclosed |
| US-5424333-A | Anthelmintic N'-substituted-N,N'-disubstitutedhydrazines | ROHM AND HAAS COMPANY (US) | 1995-06-13 | — | — | US | disclosed |
| US-5354762-A | Insecticides | ROHM AND HAAS COMPANY (US) | 1994-10-11 | — | — | US | disclosed |
| EP-0361645-B1 | ORGANIC HYDRAZINE DERIVATIVES FOR PHARMACEUTICAL USE | ROHM AND HAAS COMPANY (US) | 1993-09-29 | — | — | EP | disclosed |
| EP-0261755-B1 | FIVE-MEMBERED HETEROCYCLIC DERIVATIVES OF N'-SUBSTITUTED-N,N'-DIACYLHYDRAZINES | ROHM AND HAAS COMPANY (US) | 1992-12-16 | — | — | EP | disclosed |
| US-5117057-A | Insecticidal N' substituted-N-N'-disubstituted-hydrazines | ROHM AND HAAS COMPANY (US) | 1992-05-26 | — | — | US | disclosed |
| EP-0253468-B1 | SIX-MEMBERED HETEROCYCLIC DERIVATIVES OF N'SUBSTITUTED-N,N'-DIACYLHYDRAZINES | ROHM AND HAAS COMPANY (US) | 1991-11-06 | — | — | EP | disclosed |
| EP-0361645-A2 | Organic hydrazine derivatives for pharmaceutical use | ROHM AND HAAS COMPANY (US) | 1990-04-04 | — | — | EP | disclosed |
| EP-0261755-A2 | Five-membered heterocyclic derivatives of N'-substituted-N,N'-Diacylhydrazines | ROHM AND HAAS COMPANY (US) | 1988-03-30 | — | — | EP | disclosed |
| EP-0253468-A2 | Six-membered heterocyclic derivatives of N'substituted-N,N'-diacylhydrazines | ROHM AND HAAS COMPANY (US) | 1988-01-20 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170174619-A1 | HDAC INHIBITOR COMPOUNDS AND METHODS OF TREATMENT | HDAC4, HDAC1, HDAC5 | ALDH1A1 168/4885GAA 436/4885HDAC1 2/4885 |
| US-11731934-B2 | HDAC inhibitor compounds and methods of treatment | HDAC4, HDAC1, HDAC5 | ALDH1A1 168/4885GAA 436/4885HDAC1 2/4885 |
| US-20210009509-A1 | HDAC INHIBITOR COMPOUNDS AND METHODS OF TREATMENT | HDAC4, HDAC1, HDAC5 | ALDH1A1 168/4885GAA 436/4885HDAC1 2/4885 |
| US-10807944-B2 | HDAC inhibitor compounds and methods of treatment | HDAC4, HDAC1, HDAC5 | ALDH1A1 168/4885GAA 436/4885HDAC1 2/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.